Nitrofurantoin Prophylaxis for Bacteriuria and Urinary Tract Infection in Children With Neurogenic Bladder on Intermittent Catheterization

Schlager, Theresa A.; Anderson, Susan; Trudell, Julie; Hendley, J. Owen

doi:10.1016/s0022-5347(01)62651-x

Cited by 10 publications

(11 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Oral prophylaxis is limited to agents with the lowest risk of long-term side effects, like nitrofurantoin or TMP/sulfa. However, the downside of daily prophylaxis is an increased likelihood of selecting antibiotic-resistant organisms [19,20,21,22]. The use of cranberry juice in this population does not appear to be effective in reducing colonization or UTIs [23].…”

Section: Recurrent Urinary Infectionsmentioning

confidence: 94%

Nonsurgical Management of the Neurogenic Bladder in Children

Kryger

2008

The Scientific World JOURNAL

View full text Add to dashboard Cite

The neurogenic bladder can have many serious consequences. However, with proper understanding of the disease spectrum, and with proper awareness of the surveillance and management tools, adverse outcomes can be minimized. The incidence of renal failure is uncommon. With proper medical therapy, one can achieve continence and minimize the risk of symptomatic urinary tract infections. There are a number of nonsurgical strategies described that can help in the management of the neurogenic bladder.

show abstract

Section: Recurrent Urinary Infectionsmentioning

confidence: 94%

Nonsurgical Management of the Neurogenic Bladder in Children

Kryger

2008

The Scientific World JOURNAL

View full text Add to dashboard Cite

show abstract

“…It remains a big issue whether prophylactic antibiotics can prevent bacteriuria and UTI in patients performing clean intermittent selfcatheterization due to neurogenic bladder. Two double-blind, placebo-controlled, crossover trials showed that nitrofurantoin prophylaxis could reduce the risk of bacteriuria and UTI significantly [41,42]. On the contrary, a Cochrane systematic review demonstrated that the evidence failed to prove the certain benefits of antibiotic prophylaxis in patients with clean intermittent self-catheterization [43].…”

Section: Neurogenic Bladdermentioning

confidence: 99%

Management of Complicated Urinary Tract Infection

Pang¹,

Deng²,

Zhou³

2018

Urinary Tract Infection - The Result of the Strength of the Pathogen, or the Weakness of the Host

View full text Add to dashboard Cite

The management of complicated urinary tract infection (UTI) remains a challenge since the coexisted conditions may significantly decrease the successful rate of treatment. In this chapter, the specific conditions including indwelling catheter, urolithiasis, neurogenic bladder, vesicoureteral reflux and pregnancy are listed. In terms of each condition, the potential influence on UTI and management strategy is discussed. Not only is the current evidence reviewed but also we present our experience on management of complicated UTI.

show abstract

“…Nitrofurantoin, 1-{[(5-nitro-2-furanyl)methylene]amino}-2, 4-imidazolidinedione, is used for the treatment of urinary tract infections (Schlager et al, 1998;Cahen & Honderlick, 2000;Rogers et al, 2004). As with other nitro drugs, the bactericidal activity of nitrofurantoin requires nitroreduction.…”

Section: Introductionmentioning

confidence: 99%

Effects of Piperitone on the Antimicrobial Activity of Nitrofurantoin and on Nitrofurantoin Metabolism byEnterobacter cloacae.

Abdolpour

Shahverdi

Rafii

et al. 2007

Pharmaceutical Biology

View full text Add to dashboard Cite

Monoterpenes, including piperitone, increase nitrofurantoin susceptibility in members of the family Enterobacteriaceae. To understand interactions of these compounds, a nitrofurantoin-resistant clinical strain of Enterobacter cloacae was subjected to two-dimensional checkerboard dilutions of piperitone and nitrofurantoin. Synergy was demonstrated with all combinations of these compounds. HPLC analysis showed that E. cloacae metabolized nitrofurantoin to compounds that were not detectable by chromatography with UV detection and lacked bactericidal activity. E. cloacae produced a cell-associated nitroreductase, whose activity was reduced by piperitone in a dose-dependent manner. More than one mechanism may be involved in the synergistic interaction of these compounds.

show abstract

Nitrofurantoin Prophylaxis for Bacteriuria and Urinary Tract Infection in Children With Neurogenic Bladder on Intermittent Catheterization

Cited by 10 publications

References 16 publications

Nonsurgical Management of the Neurogenic Bladder in Children

Nonsurgical Management of the Neurogenic Bladder in Children

Management of Complicated Urinary Tract Infection

Effects of Piperitone on the Antimicrobial Activity of Nitrofurantoin and on Nitrofurantoin Metabolism byEnterobacter cloacae.

Contact Info

Product

Resources

About