No change in glucose tolerance and substrate oxidation after a high-carbohydrate, low-fat diet

Effects of lipoprotein lipase gene variations, a high-carbohydrate low-fat diet, and gender on serum lipid profiles in healthy Chinese Han youth

“…However, Ginsberg et al noted that "during the high carbohydrate period, plasma TG was found to increase in most subjects for 5-7 days before establishing a new plateau (19)". In a recent study, Ji (20) (22,23), the present study used an intervention of 6 days with a regular diet for 7 days as a wash-out period.…”

TaqIB polymorphism in the CETP gene modulates the impact of HC/LF diet on the HDL profile in healthy Chinese young adults

“…Previous studies have shown that after 5-7 days of HC/LF diet, serum triacylglycerol reaches a new steady state and remains constant throughout the period of the diet [24,25]. Therefore, a regime of a 7-day washout diet followed by a 6-day intervention was adopted for this study.…”

The influence of dietary fat on insulin resistance

“…1) [17]. In contrast, several studies in healthy adults have not observed any difference between high-and lowfat diets in the effect on insulin sensitivity [14][15][16]. A recent study by Bisschop et al [20] found that although a high-fat diet fed for 11 days did not have a major effect on insulin-mediated glucose disposal measured by euglycemic clamp, dietary fat substantially reduced oxidative glucose disposal while increasing nonoxidative glucose disposal relative to a high-carbohydrate diet.…”