No evidence of IGH‐MALT1 translocation in the Ma‐1 cell line

Beware imposters: MA‐1, a novel MALT lymphoma cell line, is misidentified and corresponds to Pfeiffer, a diffuse large B‐cell lymphoma cell line—A reply: Despite the same 8‐code STR, MA‐1 and Pfeiffer are cytogenetically diverse

“…Furthermore, the unique IGH/MALT1 fusion was more readily detected in MA-1.46 than in the parental MA-1 cells, suggesting that MA-1.46 is a more homogenous t(14;18) (q32;q21)/ IGH-MALT1-containing cell line. In summary, despite sharing the same STR as Pfeiffer, we provided further evidence not only to demonstrate that MA-1 and its MA-1.46 subclones are cytogenetically different from Pfeiffer cells (Capes-Davis et al, 2013b) but also to reinforce our argument to the comment of Flossbach et al (2013) (Kuo et al, 2013). We thus believe MA-1 and its MA-1.46 subclone can be useful in dissecting the molecular pathogenesis of t(14;18)(q32;q21)/IGH-MALT1containing B-cell lymphoma.…”