Nocturnal sleep duration and cognitive impairment in a population‐based study of older adults

Loerbroks, Adrian; Debling, Desiree; Amelang, Manfred; Stürmer, Til

doi:10.1002/gps.2305

Cited by 73 publications

(88 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Loerbroks and Benito-León reported that increase in sleep duration is associated with cognitive impairment in older adults (Loerbroks et al 2010;BenitoLeón et al 2009). Our findings found no association between sleep durations and dementia and are thus inconsistent with these previous findings.…”

Section: Discussionmentioning

confidence: 99%

Association of sleep quality and dementia among long-lived Chinese older adults

Yue

Huang

Wang

et al. 2012

AGE

View full text Add to dashboard Cite

In this study, we examined the existence of relationship between sleep quality and dementia in subjects aged 90 years and above. The sample included 216 men and 444 women. Dementia and sleep quality were measured with 30-item mini-mental state examination (MMSE) and the Pittsburgh sleep quality index, respectively. Subjects with dementia had higher sleep quality score (7.83 ± 2.15 vs. 5.22 ± 2.49; P < 0.0001), longer sleep latency (50.97 ± 21.33 vs. 37.61 ± 12.53; P < 0.0001), and a lower sleep efficiency percentage (73.95 ± 8.783 vs. 81.32 ± 10.21; P < 0.0001) and more likely to report poor sleep quality (25.42 vs.17.13 %; P 0 0.035). Subjects with poor sleep quality had significantly lower MMSE scores (P 0 0.007) and higher prevalence of dementia (P 0 0.042). Multiple logistic regressions were performed by adjusting clinical factors that are thought to be associated with dementia or sleep quality. We found that poor sleep quality was a risk factor for dementia (unadjusted odds ratio (OR) 1.719, 95 % confidence interval (CI) 1.138-2.597; adjusted OR 1.759, 95 % CI 1.012-3.057). There was no significant difference in MMSE scores (11.25 ± 3.40, 16.26 ± 5.14, and 15.43 ± 5.51; P 0 0.105) among participants with daily average sleep durations of <5, 5-9, and >9 h, respectively. Among Chinese nonagenarians and centenarians, dementia was correlated with poor sleep quality, longer sleep latency, and lower sleep efficiency percentage.

show abstract

Section: Discussionmentioning

confidence: 99%

Association of sleep quality and dementia among long-lived Chinese older adults

Yue

Huang

Wang

et al. 2012

AGE

View full text Add to dashboard Cite

show abstract

“…Three studies reported that decreased sleep duration over time was associated with lower cognitive function [61,68,73] , and 4 studies found that increased sleep duration was related to worse cognition [59,61,68,73] . One of these studies included prospective data on cognitive function, enabling analyses of changes in sleep duration with cognitive decline; however, there was no indication of association in these results [73] .…”

Section: Results Of Studies On Change In Sleep Duration and Cognitivementioning

confidence: 99%

“…Most studies included both women and men [16, 50, 51, 54, 56-69, 71, 72, 74, 76-80] , although some studies focused on women only [55,70,73] or men only [53,75] ; 1 study did not specify the sex of participants [52] . Studies generally specified age thresholds for participants at the time of first cognitive interview: ≥ 30 years [50] , ≥ 45 years [80] , ≥ 50 years [74, 76,77] , ≥ 55 years [16] , ≥59 years [71], ≥ 60 years [54,58,60,65] , ≥ 65 years [55, 62-64, 66, 68, 69, 75] , ≥68 years [70], and ≥ 70 years [59,73,79] . Other studies provided the mean age [67] or age ranges [51-53, 56, 57, 61, 72, 78] of their participants, but did not explicitly describe an age threshold as part of the inclusion criteria; regardless, older adults were eligible for all studies.…”

Section: Study Populationmentioning

confidence: 99%

“…These studies ranged in size from 26 to 32,142 participants, and were conducted across multiple countries: United States [53, 55-57, 67, 70, 72, 73, 75, 79] , United Kingdom [61,64,77] , Spain [58,69] , Finland [50,68] , France [54,62] , Japan [65,78] , Australia [52] , Germany [59] , Ireland [16] , Netherlands [80] , Hong Kong [66] , Canada [63] , Korea [60] , China [76] , Singapore [71] . There was also a multi-country study incorporating data from China, Ghana, India, South Africa, Russia, and Mexico [74] ; the location of one study was unknown [51] .…”

Section: Description Of Studies Included In Our Reviewmentioning

confidence: 99%

See 1 more Smart Citation

Sleep Duration in Relation to Cognitive Function among Older Adults: A Systematic Review of Observational Studies

2016

View full text Add to dashboard Cite

Context: Increasing evidence suggests that circadian and sleep parameters influence cognitive function with aging. Objective: To evaluate observational studies of sleep duration and cognition in older adults. Data Sources: A systematic review of OVID Medline and PsycINFO through September 2015, and review of bibliographies from studies identified. Study Selection: English-language articles reporting observational studies of sleep duration and cognitive function in older populations. Data Extraction: Data extraction by 2 authors using predefined categories of desired information. Results: Thirty-two studies met our inclusion criteria, with nearly two-thirds published in the past 4 years. One-third of studies indicated that extreme sleep durations were associated with worse cognition in older adults. More studies favored an association with long vs. short sleep durations (35 vs. 26% of studies, respectively). Four studies found that greater changes in sleep duration over time were related to lower cognition. Study design and analytic methods were very heterogeneous across studies; therefore, meta-analysis was not undertaken. Limitations: We reviewed English-language manuscripts only, with a qualitative summary of studies identified. Conclusions and Implications of Key Findings: Observational studies of sleep duration and cognitive function in older adults have produced mixed results, with more studies suggesting that long (rather than short) sleep durations are related to worse cognition. Studies more consistently indicate that greater changes in sleep duration are associated with poor cognition. Future studies should be prospectively designed, with objective sleep assessment and longer follow-up periods; intervention studies are also needed to identify strategies for promoting cognitive health with aging.

show abstract

“…After reviewing the full texts of the remaining 30 articles, 20 articles were excluded because of the following reasons: not relevant to our analysis ( n = 5) [14,17,[21][22][23], insufficient data ( n = 11) [12,15,16,[24][25][26][27][28][29][30][31] , shared an identical study population with other articles ( n = 1) [19], data from preexisting dementia [32] , using dementia mortality as a result [33] , and using an acute biomarker as exposure [34] . The remaining 10 studies (3 case-control studies [10,11,35] and 7 cohort studies [36][37][38][39][40][41][42] were included in the final analysis.…”

Section: Statistical Analysesmentioning

confidence: 99%

Longer Duration of Sleep and Risk of Cognitive Decline: A Meta-Analysis of Observational Studies

Kim

Myung²,

Lee³

et al. 2016

Neuroepidemiology

View full text Add to dashboard Cite

Background: Previous observational epidemiological studies have reported inconsistent findings about the association between longer durations of sleep and the risk of cognitive impairment and dementia. To investigate the association between longer durations of sleep and the risk of cognitive decline, we performed a meta-analysis of observational studies. Methods: We searched PubMed, EMBASE, and the bibliographies of relevant articles to retrieve additional studies in July 2015. A total of 53,942 participants (mean age 66.9 years) were included in the final analysis. Three evaluators independently reviewed and selected articles, based on pre-determined selection criteria. Results: Among a total of 695 articles, 10 observational epidemiological studies with 3 case-control studies and 7 cohort studies were included in the final analysis. Compared to the average sleep duration, the odds ratio or relative risk of the longest sleep duration was 1.42 (95% CI 1.27-1.59) for cognitive decline in the fixed-effect meta-analysis, 1.38 for cognitive impairment (95% CI 1.23-1.56), and 1.42 for dementia (95% CI 1.15-1.77). Subgroup meta-analyses by various factors such as study design, type of cognitive decline, gender, region, age, and methodological quality of study showed consistent findings. Conclusion: The current meta-analysis found that longer duration of sleep is associated with an increased risk of cognitive decline.

show abstract

Nocturnal sleep duration and cognitive impairment in a population‐based study of older adults

Abstract: Increases in sleep duration are associated with cognitive impairment. A biological explanation for this association is currently lacking. Increases in sleep duration could be a marker of cognitive deficits.

Cited by 73 publications

References 48 publications

Association of sleep quality and dementia among long-lived Chinese older adults

Association of sleep quality and dementia among long-lived Chinese older adults

Sleep Duration in Relation to Cognitive Function among Older Adults: A Systematic Review of Observational Studies

Longer Duration of Sleep and Risk of Cognitive Decline: A Meta-Analysis of Observational Studies

Contact Info

Product

Resources

About