Non-Contact Simultaneous Measurement of Thickness and Acoustic Properties of a Biological Tissue Using Focused Wave in a Scanning Acoustic Microscope

Abstract

It was verified that the frequency dependence of magnitude and phase of the reflection coefficient gave characteristic patterns against the specimen thickness, so that specimen thickness could be determined by analysis of those characteristic patterns. As a result, attenuation constant and sound speed in thin tissue specimens were determined with a non-contact procedure using a scanning acoustic microscope.

Ultrasonic tissue characterization of infarcted myocardium by scanning acoustic microscopy

“…The thickness corresponds to quency-dependent characteristics of the amplitude and f-f wavelength, so the principle of interference can be the phase of the received signals obtained at the same used. Consequently, the reflection coefficient freposition for each of the 16 frames (Okawai et al 1987, quency characteristics exhibit a unique pattern, de-1988). The slope of attenuation and the sound speed pending upon tissue thickness.…”

“…The accuracy of the method was considered to be sufficient to discuss the quantitative values of the biological specimens. A linear frequency dependence of the attenuation, in the ultrasonic frequency range of 100-200 MHz, was obtained from consideration of the interference of sound wave components (Okawai et al 1987). The data of slope of attenuation and sound speed thus obtained were converted into color signals that corresponded to the values of the amplitude and phase, and were displayed on a color monitor as two-dimensional distribution patterns.…”

“…A specially developed scanning acoustic microscope (SAM) system (Okawai et al 1987(Okawai et al ,1988Saijo et al 1991) has been used to determine quantitatively the ultrasonic properties of the infarcted myocardium,…”

Non-mineralized fibrocartilage shows the lowest elastic modulus in the rabbit supraspinatus tendon insertion: Measurement with scanning acoustic microscopy

“…14,15 This system consists of 5 parts, viz. (1) ultrasonic transducers, (2) a mechanical scanner, (3) an analogue signal processor, (4) an image signal processor, and (5) a display unit ( Figure 1).…”

Ultrasonic Tissue Characterization of Renal Cell Carcinoma Tissue

“…The region of interest for acoustic microscopy was determined after observation of the optical microscopic image. Figure 1 is a block diagram of the SAM system [7,8] which is made up of five parts: (1) ultrasonic transducer: (2) mechanical scan ner: (3) analogue signal processor; (4) image signal processor, and (5) display unit. The transducer is oscillated in the x-axis, and sample holder is scanned in the y-axis.…”