Non-Sunscreen Photoprotection: Antioxidants Add Value to a Sunscreen

Matsui, Mary S.; Hsia, Andrew; Miller, Janine D.; Hanneman, Kaija K.; Scull, Heather; Cooper, Kevin D.; Baron, Elma D.

doi:10.1038/jidsymp.2009.14

Cited by 120 publications

(88 citation statements)

References 23 publications

(23 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[168] On the other hand, the natural skin care products are safe, quickly absorbed by the skin and are hypoallergenic in nature. [169] Plant extracts are considered safe, [170] because of the simple fact that they come from nature. [171] In addition, the natural herbs have despicable mammalian toxicity and can be handled safely.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Garg

2017

IJGP

View full text Add to dashboard Cite

Skin ageing is a complex multifactorial process occurring in all living beings. It generally comprises two independent and distinct processes, i.e., intrinsic, age-dependent or chronological aging and premature aging, or photoaging which is the result of undue exposure of the skin to ultraviolet (UV) radiations. Photoaging can be prevented or the effects of photoaging can be reduced by the use of certain anti-aging and anti-wrinkle agents. The extracellular matrix (ECM) which forms the outermost part of skin comprises fibroblasts and proteins such as collagen and elastin. Degradation of ECM is directly linked to skin aging and is responsible for the increase in activity of certain enzymes such as collagenase, elastase, and hyaluronidase (HYAL) that are involved in skin aging. With aging there is decrease in the levels of elastin, collagen, and hyaluronic acid which leads to loss of strength and flexibility of skin and appear as wrinkles on the skin. Further, the increase in the activity of collagenase, elastase, and HYAL is triggered by the high levels of reactive oxygen species produced when the skin is exposed to excessive UV radiations leading to skin aging. Today, in the age of modern science and advanced technology, although many techniques such as laser rejuvenation, plastic surgery, and lots of synthetic products such as sunscreen lotions, creams are available yet, there is a place for natural, herbal anti-aging cosmetics. Various botanical extracts have the power to reduce the appearance of skin aging and enhance the beauty of the skin. Medicinal plants have several phytoconstituents such as polyphenols, alkaloids, tannins, saponins, carotenoids, and terpenoids which possess antioxidant properties and can be used in treating the signs of aging. Some plants contain phenolic compounds which have free-radical scavenging property and can suppress aging. Some plants or their extracts possess several other constituents that may have the capability of inhibiting various enzyme such as HYAL, elastase, and matrix metalloproteinases enzyme that play a major role in skin aging. Some of them may possess the free radical scavenging or antioxidant property to fight against the signs of aging. This review focuses on the compilation of medicinal plants and natural compounds as anti-aging and anti-wrinkling agents along with their chemical constituents based on their possible molecular mechanism of action. The present review will facilitate the scientists working in this area for the development of new anti-aging and anti-wrinkle formulations with better efficiency and safety.

show abstract

Section: Discussionmentioning

confidence: 99%

Untitled

Garg

2017

IJGP

View full text Add to dashboard Cite

show abstract

“…O uso de antioxidantes, como flavonoides, por exemplo, compostos comumente encontrados em vegetais com a função de protegê-los contra radiação UV, poderia apresentar papel sinérgico e complementar os filtros solares, atuando na proteção solar (8,(14)(15)(16)(17). Alguns estudos já demonstraram evidências favoráveis com relação ao uso de óleos e extratos vegetais em formulações voltadas à proteção solar (8,17,18).…”

Section: Murumuru (Astrocaryum Murumuru)unclassified

“…Na tentativa de encontrar ingredientes alternativos e com ação fotoprotetora para aplicação em cosméticos, ocorreu sensível aumento nos estudos envolvendo compostos de origem natural. A estratégia de investigação de novos compostos envolve potencial ação antioxidante e/ou presença de cromóforos em sua molécula que them against UV radiation, could provide synergistic and complementary role in sunscreens for improved sun protection (8,(14)(15)(16)(17). Some studies have shown favourable evidence regarding the use of oils and plant extracts in formulations aimed at sun protection (8,17,18).…”

Section: Introductionunclassified

Comparison of sunscreens Containing Titanium Dioxide Alone Or In Association With Cocoa, Murumuru Or Cupuaçu Butters

Marronato

Almeida

Mota

et al. 2016

BBR

View full text Add to dashboard Cite

Biopharmaceutical Sciences│Ciências BiofarmacêuticasBiomed Biopharm Res. , 2016; (13) 2: , 229-244 229 Biomedical and Biopharmaceutical Research J o r n a l d e I n v e s t i g a ç ã o B i o m é d i c a e B i o f a r m a c ê u t i c a Comparison of sunscreens Containing Titanium Dioxide Alone Or In AssociationWith Cocoa, Murumuru Or Cupuaçu Butters AbstractIngredients of natural origin may represent alternatives for formulating sunscreens, without compromising their effectiveness. The literature has shown the antioxidant potential of compounds existing in murumuru (Astrocaryum murmuru), cupuaçu (Theobroma grandiflorum) and cocoa (Theobroma cacao) butters that recommends further investigation. The objectives of this research were: (1) to develop bioactive photoprotective formulations containing cocoa, murmuru or cupuaçu butters in association with a physical sunscreen (titanium dioxide (TiO2)) and (2) determine the possible photoprotective activity of butters and their interactions with the sunscreen. Cocoa, cupuaçu and murumuru butter were individually associated to TiO2 in O / W emulsions. The anti-UVA and UVB efficacy in vitro was estimated by diffuse transmittance analysis in a Labsphere® UV2000S, using quartz plates and Transpore® tape to obtain the SPF (sun protection factor) and critical wavelength. Photoprotective formulations containing titanium dioxide and bioactive butters were obtained using Aristoflex® AVC and triglycerides of caprylic capric acid (GTCC). The SPF of the samples containing only TiO2 and formulations containing cocoa, murumuru or cupuassu butters associated with TiO2 ranged from 4 to 5. The critical wavelength values for these formulations ranged from 383.0 to 386.7 nm. The results indicated no increase in the SPF value for formulations containing vegetable butters. The critical wavelength values indicated their potential to absorb part of the UVA radiation.Keywords: titanium dioxide, bioactive butters, Theobroma cacao, Theobroma grandiflorum, Astrocaryum murumuru, in vitro SPF ResumoOs ingredientes de origem natural podem representar alternativas para formulação de protetores solares, sem que haja comprometimento de sua eficácia. A literatura tem indicado potencial antioxidante de compostos existentes nas manteigas de murumuru (Astrocaryum murumuru), cupuaçu (Theobroma grandiflorum) e cacau (Theobroma cacao) que necessitam de maior investigação. Os objetivos desta pesquisa foram: (1) desenvolver fotoprotetores bioativos contendo manteigas de cacau (Theobroma cacao), murumuru (Astrocaryum murumuru) ou cupuaçu (Theobroma grandiflorum (Willd. Ex. Spring) Schum) em associação com filtro solar físico (dióxido de titânio) e (2) determinar a possível atividade fotoprotetora das manteigas e suas interações com filtro solar. As manteigas de cacau, cupuaçu e murumuru foram associadas, individualmente, ao dióxido de titânio em emulsões O/A. A eficácia anti-UVA e UVB in vitro foi estimada por meio da análise de transmitância difusa realizada em Labsphere® UV2000S utilizando placas de quartzo ...

show abstract

“…Antioxidants are commonly added in commercial sunscreen preparationsin order to reduce the photo-oxidative damage that results from UV-induced ROS production, providing a sort of non-sunscreen photo-protection and supplement the photoprotective effects of sunscreens [8]. These include several well characterized vitamins including vitamins C, E and β-carotene [9].…”

Section: Antioxidantsmentioning

confidence: 99%

Sunscreens and Antioxidants as Photo-protective Measures: An update

Hassan¹,

Dorjay²,

Sami³

et al. 2013

Our Dermatol Online

View full text Add to dashboard Cite

There are many photo-protective measures adopted for protection from the solar radiation especially the UV radiation spectrum, sunscreens being the main agents. Besides the traditional approach of topical use of sunscreens, both chemical and physical, a new approach has emerged to use systemic agents in the form of vitamins and minerals. In this review, we are describing the major aspects related to sunscreens and anti-oxidants as photo-protective measures.

show abstract

Non-Sunscreen Photoprotection: Antioxidants Add Value to a Sunscreen

Cited by 120 publications

References 23 publications

Untitled

Untitled

Comparison of sunscreens Containing Titanium Dioxide Alone Or In Association With Cocoa, Murumuru Or Cupuaçu Butters

Sunscreens and Antioxidants as Photo-protective Measures: An update

Contact Info

Product

Resources

About