Nonalcoholic fatty liver disease and its association with cardiovascular disease

Prevalence and predictors of alanine aminotransferase elevation among normal weight, overweight and obese youth in Mexico

“…A goal of this study was to identify specific clinical measures, in addition to ALT, that could be used to determine which youth in Mexico may be at greater risk of developing NAFLD. In addition to the increased risk of chronic liver disease there is growing evidence that NAFLD may be linked to other severe diseases, including diabetes and cardiovascular disease . Monitoring metabolic factors among at‐risk youth may help to prevent the occurrence of these chronic diseases in the future.…”

Assessment of atherosclerosis in obese adolescents: Positive correlation of mean platelet volume and carotid intima media thickness

“…There are some studies about the MPV levels in obesity in the literature. Regarding that cardiovascular disease is one of the most common causes of morbidity and mortality in NAFLD patients, 39 MPV may, in part, help to determine atherosclerosis risk in this group of patients. These authors suggested that higher MPV levels in obese individuals might be a possible cause for increased risk of atherosclerosis.…”

Mean Platelet Volume in Obese Adolescents with Nonalcoholic Fatty Liver Disease

“…Mean platelet volume, which is a parameter generated by full blood count analyzers as part of the routine complete blood count test cycle, has recently become an interesting topic in cardiovascular research [29][30][31][32] . The use of this parameter adds no extra cost and technical effort especially with regard to the fact that cardiovascular disease is the second most common cause of death in NAFLD patients 33 , MPV may help the early diagnosis of atherosclerosis in this group of patients.…”