Purpose
Spatial position accuracy in magnetic resonance imaging (MRI) is an important
concern for a variety of applications, including radiation therapy planning, surgical
planning, and longitudinal studies of morphologic changes to study neurodegenerative
diseases. Spatial accuracy is strongly influenced by gradient linearity. This work
presents a method for characterizing the gradient non-linearity fields on a per-system
basis, and using this information to provide improved and higher-order (9th vs 5th)
spherical harmonic coefficients for better spatial accuracy in MRI.
Methods
A large fiducial phantom containing 5229 water-filled spheres in a grid pattern
is scanned with the MR system, and the positions all the fiducials are measured and
compared to the corresponding ground truth fiducial positions as reported from a
computed tomography (CT) scan of the object. Systematic errors from off-resonance (i.e.,
B0) effects are minimized with the use of increased receiver bandwidth (±125
kHz) and two acquisitions with reversed readout gradient polarity. The spherical
harmonic coefficients are estimated using an iterative process, and can be subsequently
used to correct for gradient non-linearity. Test-retest stability was assessed with five
repeated measurements on a single scanner, and cross-scanner variation on four
different, identically-configured 3T wide-bore systems.
Results
A decrease in the root-mean-square error (RMSE) over a 50 cm diameter spherical
volume from 1.80 mm to 0.77 mm is reported here in the case of replacing the
vendor’s standard 5th order spherical harmonic coefficients with custom fitted
9th order coefficients, and from 1.5mm to 1mm by extending custom fitted
5th order correction to the 9th order. Minimum RMSE varied between scanners, but was
stable with repeated measurements in the same scanner.
Conclusions
The results suggest that the proposed methods may be used on a per-system basis
to more accurately calibrate MR gradient non-linearity coefficients when compared to
vendor standard corrections.