In this paper we study quantum del Pezzo surfaces belonging to a certain class. In particular we introduce the generalised Sklyanin-Painlevé algebra and characterise its PBW/PHS/Koszul properties. This algebra contains as limiting cases the generalised Sklyanin algebra, Etingof-Ginzburg and Etingof-Oblomkov-Rains quantum del Pezzo and the quantum monodromy manifolds of the Painlevé equations.