Noninvasive brain stimulation in rehabilitation of hemispatial neglect after stroke

Veldema, Jitka; Bösl, Kathrin; Neumann, Gerd; Verheyden, Geert; Nowak, Dennis A.

doi:10.1017/s1092852918001748

Cited by 12 publications

(10 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In sum, bilateral stimulation is superior to unilateral protocols. Similarly, a previous meta-analysis demonstrates the superior effectiveness of bilateral tDCS/rTMS for improving visuo-spatial ability following stroke [ 39 ]. However, a current meta-analysis indicates that bilateral tDCS is inferior to unilateral tDCS for improving motor learning in stroke patients [ 74 ].…”

Section: Discussionmentioning

confidence: 80%

“…Despite its limitations, the theory of interhemispheric imbalance and rivalry provides the most often used theoretical framework for the application of noninvasive brain stimulation in stroke rehabilitation [ 37 ]. Previous studies have demonstrated that several stroke-induced deficiencies, such as upper limb impairment or visuo-spatial disabilities may be successfully restored by application of non-invasive brain stimulation within this concept [ 38 , 39 ]. The available data (see previous subchapter) indicates that a similar application may also be useful for supporting gait, balance, and lower limbs´ motor functioning.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke

Veldema

Gharabaghi

2022

J NeuroEngineering Rehabil

Self Cite

View full text Add to dashboard Cite

Objectives This systematic review and meta-analysis aim to summarize and analyze the available evidence of non-invasive brain stimulation/spinal cord stimulation on gait, balance and/or lower limb motor recovery in stroke patients. Methods The PubMed database was searched from its inception through to 31/03/2021 for randomized controlled trials investigating repetitive transcranial magnetic stimulation or transcranial/trans-spinal direct current/alternating current stimulation for improving gait, balance and/or lower limb motor function in stroke patients. Results Overall, 25 appropriate studies (including 657 stroke subjects) were found. The data indicates that non-invasive brain stimulation/spinal cord stimulation is effective in supporting recovery. However, the effects are inhomogeneous across studies: (1) transcranial/trans-spinal direct current/alternating current stimulation induce greater effects than repetitive transcranial magnetic stimulation, and (2) bilateral application of non-invasive brain stimulation is superior to unilateral stimulation. Conclusions The current evidence encourages further research and suggests that more individualized approaches are necessary for increasing effect sizes in stroke patients.

show abstract

Section: Discussionmentioning

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke

Veldema

Gharabaghi

2022

J NeuroEngineering Rehabil

Self Cite

View full text Add to dashboard Cite

show abstract

“…Meta-analyses and systematic reviews also suggest a beneficial effect of rTMS on USN. 61,63,64,66,68–71…”

Section: Augmenting Recovery: State Of the Evidence On Usn Interventionmentioning

confidence: 99%

Unilateral Spatial Neglect Recovery Poststroke

Durfee

Hillis

2023

Stroke

View full text Add to dashboard Cite

Unilateral spatial neglect (USN) is a common and disabling cognitive consequence of stroke wherein individuals demonstrate decreased response to contralesional information. Here, we provide an updated narrative review of studies that shed light on the neural mechanisms and predictors of recovery of USN. Additionally, we report a rapid review of randomized controlled trials focusing on USN intervention, both nonpharmacological and pharmacological, published in the last 5 years. Randomized controlled trials are reviewed within the context of systematic reviews and meta-analyses of USN interventions published within the same time frame. The quality of randomized controlled trials of treatment is higher compared to quality reported in previous reviews and meta-analyses. However, remaining weaknesses in participant demographic reporting, as well as small, heterogenous samples, render generalizability and cross-study interpretation a challenge. Nevertheless, evidence regarding neural mechanisms underlying USN recovery and regarding the effectiveness of targeted USN interventions is accumulating and strengthening, setting the foundation for future investigations into patient-specific factors that may influence treatment response. We identify gaps and provide suggestions for future USN intervention research.

show abstract

“…Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) techniques have been used in the past years to improve motor recovery in stroke patients, often jointly with standard physiotherapy practice. However, while at the single study level the administration of TMS and tDCS treatments appear beneficial to patients in motor and/or cognitive domain, meta-analysis results have shown that these effects are rather limited or, in some cases, even non-existent (e.g., [11][12][13][14][15]). It should be noticed that these stimulation protocols have been developed on the basis of the conviction that either the interhemispheric competition or the vicariation model might be the one that best predicts recovery [9].…”

Section: Stroke Recovery Models and Efficiency Of Non-invasive Rehabilitation Protocolsmentioning

confidence: 99%

A New Framework to Interpret Individual Inter-Hemispheric Compensatory Communication after Stroke

Brancaccio

Tabarelli

Belardinelli

2022

JPM

View full text Add to dashboard Cite

Stroke constitutes the main cause of adult disability worldwide. Even after application of standard rehabilitation protocols, the majority of patients still show relevant motor impairment. Outcomes of standard rehabilitation protocols have led to mixed results, suggesting that relevant factors for brain re-organization after stroke have not been considered in explanatory models. Therefore, finding a comprehensive model to optimally define patient-dependent rehabilitation protocols represents a crucial topic in clinical neuroscience. In this context, we first report on the rehabilitation models conceived thus far in the attempt of predicting stroke rehabilitation outcomes. Then, we propose a new framework to interpret results in stroke literature in the light of the latest evidence regarding: (1) the role of the callosum in inter-hemispheric communication, (2) the role of prefrontal cortices in exerting a control function, and (3) diaschisis mechanisms. These new pieces of evidence on the role of callosum can help to understand which compensatory mechanism may take place following a stroke. Moreover, depending on the individual impairment, the prefrontal control network will play different roles according to the need of high-level motor control. We believe that our new model, which includes crucial overlooked factors, will enable clinicians to better define individualized motor rehabilitation protocols.

show abstract

Noninvasive brain stimulation in rehabilitation of hemispatial neglect after stroke

Cited by 12 publications

References 44 publications

Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke

Non-invasive brain stimulation for improving gait, balance, and lower limbs motor function in stroke

Unilateral Spatial Neglect Recovery Poststroke

A New Framework to Interpret Individual Inter-Hemispheric Compensatory Communication after Stroke

Contact Info

Product

Resources

About