Noninvasive measurement of blood glucose based on optical sensing

Tamura, Kento; Fujita, Kouji; Kaneko, Wataru; Linh, Nguyen Tuong; Nishimatsu, Toyonori; Ikeda, Hiroaki; Toba, Eiji

doi:10.1109/imtc.2004.1351473

Cited by 4 publications

(2 citation statements)

References 3 publications

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“…Here, the advent of measurement systems using fiber optic probes has made it easier to make ATR measurements on oral mucosa. In particular, some researchers have used ATR fiber probes consisting of a bare polycrystalline fiber [17], while others have developed optical fiber probes incorporating a prism made of zinc selenide (ZnSe) at the distal end [18].…”

Section: Introductionmentioning

confidence: 99%

Hollow optical-fiber based infrared spectroscopy for measurement of blood glucose level by using multi-reflection prism

Kino¹,

Omori²,

Kubo³

et al. 2016

Biomed. Opt. Express

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A mid-infrared attenuated total reflection (ATR) spectroscopy system employing hollow optical fibers and a trapezoidal multi-reflection ATR prism has been developed to measure blood glucose levels. Using a multi-reflection prism brought about higher sensitivity, and the flat and wide contact surface of the prism resulted in higher measurement reproducibility. An analysis of in vivo measurements of human inner lip mucosa revealed clear signatures of glucose in the difference spectra between ones taken during the fasting state and ones taken after ingestion of glucose solutions. A calibration plot based on the absorption peak at 1155 cm(-1) that originates from the pyranose ring structure of glucose gave measurement errors less than 20%.

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Section: Introductionmentioning

confidence: 99%

Hollow optical-fiber based infrared spectroscopy for measurement of blood glucose level by using multi-reflection prism

Kino¹,

Omori²,

Kubo³

et al. 2016

Biomed. Opt. Express

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show abstract

“…12,13 Some groups reported that they have attempted to measure blood glucose levels in vivo by using an ATR prism with MIR lasers 14,15 and an FT-IR spectrometer. 16 These methods mainly detect glucose in interstitial fluid that reflects the blood glucose level 17 because the penetration depth of MIR-ATR spectroscopy is limited to a few microns. Also, the area to be measured is limited to the finger tips because of the bulky measurement equipment.…”

Section: Introductionmentioning

confidence: 99%

Blood glucose measurement by using hollow optical fiber-based attenuated total reflection probe

2014

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Abstract. A noninvasive glucose monitoring system based on mid-infrared, attenuated total reflection spectroscopy using a hollow optical fiber probe is developed. Owing to the flexible fiber probe, measurement of oral mucosa, where blood capillaries are near the skin surface, is possible. Blood glucose levels are measured by detecting the peak intensity of glucose absorption bands, and the experimental results showed that the reproducibility of the measurement is high enough for monitoring blood glucose. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

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Dynamic Spectrum for noninvasive blood component analysis and its advances

Wang

et al. 2018

Applied Spectroscopy Reviews

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Noninvasive measurement of blood glucose based on optical sensing

Cited by 4 publications

References 3 publications

Hollow optical-fiber based infrared spectroscopy for measurement of blood glucose level by using multi-reflection prism

Hollow optical-fiber based infrared spectroscopy for measurement of blood glucose level by using multi-reflection prism

Blood glucose measurement by using hollow optical fiber-based attenuated total reflection probe

Dynamic Spectrum for noninvasive blood component analysis and its advances

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