Integrity monitoring (IM) in autonomous navigation has been extensively researched, but currently available solutions are mainly applicable to specific algorithms and sensors, or limited by linearity or 'Gaussianity' assumptions. This study investigates a Solution Separation (SS) based framework for universal IM, scalable to multi-sensor fusion as each hypothesis assumes a whole sensor measurement set as faulty. Architecturally we consider that: 1) multi sensor systems must account for various sensor noise models which lead to inconsistent estimates of uncertainties, 2) a module must be able to detect sensor failure or sensor noise mismodeling and suggest better bounds for the error, without being constantly conservative, 3) some algorithms are computationally heavy to monitor in the SS setting or the provided covariances cannot be interpreted in IM. A hybrid SS architecture can be practical, where some solutions are evaluated with a navigation algorithm with known characteristics, although the all-sensor-in solution is evaluated with the monitored algorithm. Experiments are run on filter and smoothing-based navigation algorithms. In addition, we experiment with hybrid SS monitoring and time-correlated noise to evaluate the appropriability of our framework in the context of the above-mentioned requirements. This is a novel framework in the IM domain, directly integrable in existing navigation solutions and, in our opinion, it will facilitate the quantification of the effect of different sensors in navigation safety.