Nonsteroidal Anti-inflammatory Drugs Utilization Patterns and Risk of Adverse Events due to Drug-Drug Interactions among Elderly Patients: A Study from Jordan

Al-Azayzih, Ahmad; Al‐Azzam, Sayer; Alzoubi, Karem H.; Jarab, Anan S.; Kharaba, Zelal; Al‐Rifai, Rami H.; Alnajjar, Munther S

doi:10.1016/j.jsps.2020.03.001

Cited by 25 publications

(21 citation statements)

References 33 publications

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“…Al-Azayzih et al stated that among elderly patients, diclofenac sodium was the most commonly prescribed non-aspirin NSAID (25.1%) followed by ibuprofen (3.1%). [6] Asiri et al reported that the most commonly consumed NSAID in their study was ibuprofen (45.2%). [7] In addition, Hwong et al reported that among the patients who received NSAIDs in primary care in Malaysia, diclofenac was the most commonly prescribed NSAID (40.5%).…”

Section: Discussionmentioning

confidence: 90%

“…[5] Al-Azayzih et al stated that these drugs are associated with numerous adverse effects including renal toxicity, gastrointestinal bleeding, and ulcer mainly among elderly patients. [6] Asiri et al conducted a questionnaire among Saudi population and reported that more than 65% of the participants agreed that they have taken NSAIDs and that 6.7% of them taking it regularly. [7] They also said that the frequency of taking NSAIDs without a medical prescription was 45.5%.…”

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confidence: 99%

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Ahmed¹

2021

AJP

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Aim: This study aims to explore the frequency of prescribing nonsteroidal anti-inflammatory drugs (NSAIDs) in a public hospital in Al-Kharj. Materials and Methods: This study included review the electronic medical records of outpatients who received at least one of the NSAIDs between January 1, 2018, and June 30, 2018, in a public hospital in Al-Kharj. Results: The most commonly prescribe NSAIDs was diclofenac (61.23%) followed by ibuprofen (36.12%). About half of the patients receiving NSAIDs were <30 years old (50.17%) and about 72.25% of them were <40 years old. Only diclofenac was prescribed as a topical form (gel, cream, or ointment). More than 71% of diclofenac prescriptions were included a topical dosage form. Conclusion: The study showed that nonaspirin NSAIDs prescribing rate was high, particularly diclofenac and ibuprofen. It is important to increase the awareness of health-care providers to increase the efficacy and decrease the adverse effects of these medications.

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Section: Discussionmentioning

confidence: 90%

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confidence: 99%

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Ahmed¹

2021

AJP

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“…IECA (FORMICA et al, 2018), diuréticos, varfarina e antiplaquetários (AL-AZAYZIH et al, 2020). Constatou-se um uso frequente desses medicamentos 3 meses antes da admissão hospitalar por LRA, e o número de medicamentos nefrotóxicos que o paciente foi exposto foi diretamente proporcional a casos mais graves de LRA (YOKOTA; SAMPAIO; ROCHA, 2020).…”

Section: Resultsunclassified

Quando O Trabalho Adoece: Síndrome De Burnout Em Enfermeiros Da Atenção Básica De Saúde

Rodrigues¹,

Nascimento²

2021

Ciências Médicas: Campo Teórico, Métodos, Aplicabilidade E Limitações 4

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Direitos para esta edição cedidos à Atena Editora pelos autores. Open access publication by Atena Editora Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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“…Wśród często stosowanych leków o udokumentowanym niekorzystnym wpływie na funkcję wydalniczą nerek znajdują się m.in. niesteroidowe leki przeciwzapalne (NLPZ), leki układu sercowo-naczyniowego, antybiotyki, leki psychotropowe, leki przeciwwirusowe czy inhibitory pompy protonowej [15][16][17][18][19][20]. Stosowanie na co dzień wielu leków przez osoby powyżej 65 r.ż.…”

Section: Funkcja Wydalnicza Nerekunclassified

Polypragmasy as a therapeutic problem among palliative and geriatric patients

Czarkowski¹,

Bisch²,

Mleczko³

et al. 2021

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Polipragmazja jest globalnym problemem terapeutycznym różnie definiowanym przez środowiska medyczne. Pomimo braku jednoznacznego opisu tego zjawiska, wykładnią zawsze jest nieprawidłowe stosowanie farmaceutyków. Na jej negatywne skutki narażeni są przede wszystkim starsi pacjenci. Jak pokazują badania, w ostatnich latach wzrasta liczba osób powyżej 65 r.ż. Korzystają one z opieki geriatrycznej oraz stanowią ok. 85% pacjentów ośrodków paliatywnych. Cierpią z powodu wielu chorób przewlekłych i poddawane są terapii wielolekowej, której efektem są powikłania: pogorszenie funkcji wydalniczej nerek, zwiększenie ryzyka upadków i złamań, zaburzenie kontroli terapii antykoagulacyjnej prowadzące do wystąpienia powikłań krwotocznych oraz zakrzepowych czy nasilenie się problemów nietrzymania moczu. Lekarz zanim zdecyduje się na prowadzenie terapii wielolekowej, powinien ocenić stosunek przewidywanych korzyści do ryzyka efektów ubocznych. Musi również pamiętać, iż ilość przepisywanych leków dodatnio koreluje z nieprzestrzeganiem zaleceń lekarskich. Aby uniknąć błędów w planowaniu leczenia, można posługiwać się ogólnodostępnymi narzędziami: kryteriami Beers'a, kryteriami STOPP/ START oraz informacjami z platformy internetowej KtoMaLek.

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Nonsteroidal Anti-inflammatory Drugs Utilization Patterns and Risk of Adverse Events due to Drug-Drug Interactions among Elderly Patients: A Study from Jordan

Cited by 25 publications

References 33 publications

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Untitled

Quando O Trabalho Adoece: Síndrome De Burnout Em Enfermeiros Da Atenção Básica De Saúde

Polypragmasy as a therapeutic problem among palliative and geriatric patients

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