2023
DOI: 10.1002/clt2.12292
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Novel, computational IgE‐clustering in a population‐based cross‐sectional study: Mapping the allergy burden

Rebecca Czolk,
Maria Ruiz‐Castell,
Oliver Hunewald
et al.

Abstract: BackgroundEven though the prevalence of allergies is increasing, population‐based data are still scarce. As a read‐out for chronic inflammatory information, new methods are needed to integrate individual biological measurements and lifestyle parameters to mitigate the consequences and costs of allergic burden for society.MethodsMore than 480.000 data points were collected from 1462 Luxembourg adults during the representative, cross‐sectional European Health Examination Survey, spanning health and lifestyle rep… Show more

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“…Furry animals are an important source of indoor allergens, leading to high sensitization rates and the risk to develop an IgE-mediated allergic disease such as allergic rhinitis or asthma. In the general adult population, sensitization rates of 10 – 14% were found in Europe and the United States [ 1 , 2 , 3 , 4 ]. In sensitized individuals, exposure to high levels of animal allergens was associated with an increased prevalence of asthma and asthma morbidity [ 1 ].…”
Section: Introductionmentioning
confidence: 99%
“…Furry animals are an important source of indoor allergens, leading to high sensitization rates and the risk to develop an IgE-mediated allergic disease such as allergic rhinitis or asthma. In the general adult population, sensitization rates of 10 – 14% were found in Europe and the United States [ 1 , 2 , 3 , 4 ]. In sensitized individuals, exposure to high levels of animal allergens was associated with an increased prevalence of asthma and asthma morbidity [ 1 ].…”
Section: Introductionmentioning
confidence: 99%