Novel developments in non-invasive imaging of peripheral arterial disease with CT: experience with state-of-the-art, ultra-high-resolution CT and subtraction imaging

Tanaka, Ryoichi; Yoshioka, Kunihiro; Takagi, Hidenobu; Schuijf, Joanne D.; Arakita, Kazumasa

doi:10.1016/j.crad.2018.03.002

Cited by 38 publications

(23 citation statements)

References 22 publications

(17 reference statements)

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“…Compared with conventional HRCT scanners, the advantages of U-HRCT scanners used in daily clinical care were first reported for vascular imaging, with advantages such as clear visualization of very small intracranial arteries and coronary arteries, and in addition, the artery of Adamkiewicz. [18][19][20][21][22] The advantages of U-HRCT scanners for temporal bone imaging were also reported, with advantages such as increased detail of the normal structures of the middle ear. 25 The improvement in visualization of small vessels/structures as provided by U-HRCT scanners over conventional HRCT scanners is based on an improved spatial resolution by a detector of a very small size.…”

Section: Discussionmentioning

confidence: 99%

“…Ultra-high-resolution CT (U-HRCT) scanners with ultrasmall detector elements (0.25 × 0.25 mm) have recently been introduced into clinical practice. [14][15][16][17][18][19][20][21][22] The size of the detector element in the U-HRCT scanner is 50% smaller than those in conventional HRCT scanners in all 3 directions (x, y, and z axes). Use of the ultra-small detector along with an ultra-small focal spot provided by the X-ray tube obtains the highest spatial resolution in CT images, as evidenced by improved visualization of small lung lesions and small vessels in the brain and body.…”

Section: Introductionmentioning

confidence: 99%

“…Use of the ultra-small detector along with an ultra-small focal spot provided by the X-ray tube obtains the highest spatial resolution in CT images, as evidenced by improved visualization of small lung lesions and small vessels in the brain and body. [14][15][16][17][18][19][20][21][22] Honda et al have reported that U-HRCT clearly depicts small emphysematous lesions in human cadaveric lungs, which were unclear on conventional HRCT scans. 17 However, to our best knowledge, no published data are available on the advantages of the U-HRCT scanner for visualization of pulmonary emphysema in the human body, with regard to statistical differences between quantitative measurements of emphysematous lesions on U-HRCT scans versus conventional HRCT scans.…”

Section: Introductionmentioning

confidence: 99%

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<p>Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans</p>

Xu¹,

Yamashiro²,

Moriya³

et al. 2019

COPD

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To evaluate the advantages of ultra-high-resolution computed tomography (U-HRCT) scans for the quantitative measurement of emphysematous lesions over conventional HRCT scans. Materials and methods: This study included 32 smokers under routine clinical care who underwent chest CT performed by a U-HRCT scanner. Chronic obstructive pulmonary disease (COPD) was diagnosed in 13 of the 32 participants. Scan data were reconstructed by 2 different protocols: i) U-HRCT mode with a 1024×1024 matrix and 0.25-mm slice thickness and ii) conventional HRCT mode with a 512×512 matrix and 0.5-mm slice thickness. On both types of scans, lesions of emphysema were quantitatively assessed as percentage of low attenuation volume (LAV%, <−950 Hounsfield units). LAV% values determined for scan data from the U-HRCT and conventional HRCT modes were compared by the Wilcoxon matched-pairs signed rank test. The association between LAV% and forced expiratory volume in 1 s per forced vital capacity (FEV 1 /FVC) was assessed by the Spearman rank correlation test. Results: Mean values for LAV% determined for the U-HRCT and conventional HRCT modes were 8.9 ± 8.8% and 7.3 ± 8.4%, respectively (P<0.0001). The correlation coefficients for LAV% and FEV 1 /FVC on the U-HRCT and conventional HRCT modes were 0.50 and 0.49, respectively (both P<0.01). Conclusion: Compared with conventional HRCT scans, U-HRCT scans reveal emphysematous lesions in greater detail, and provide slightly increased correlation with airflow limitation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans</p>

Xu¹,

Yamashiro²,

Moriya³

et al. 2019

COPD

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“…Ultra-high-resolution computed tomography (U-HRCT) scanning with ultra-small detector elements (0.25 Â 0.25 mm) is currently achievable using the 160-row U-HRCT scanner (Aquilion Precision V R ; Canon Medical Systems, Tochigi, Japan) [8]. U-HRCT affords better spatial resolution than multi-detector row CT, and has been successfully introduced into clinical use, for example, for imaging small lung lesions and small vessels in the brain and body [9][10][11].…”

Section: Introductionmentioning

confidence: 99%

Measurement of stapes footplate thickness in otosclerosis by ultra-high-resolution computed tomography

Akazawa

Ganaha

Higa

et al. 2020

Acta Oto-Laryngologica

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Background: Ultra-high-resolution computed tomography (U-HRCT) utilizes a 1024 Â 1024 matrix with 0.25-mm section thickness, offering better spatial resolution than conventional multi-detector row CT to detect anatomic data for otologic surgery. Aims: We examined stapes footplate thickness using U-HRCT in relation to stapedotomy to predict the difficulty of the surgical procedure. Materials and methods: Subjects were 12 otosclerosis patients and 25 controls who underwent diagnostic U-HRCT. A profile curve (Hounsfield units) was used to measure stapes footplate thickness along a perpendicular line across the stapes footplate in a plane parallel to the lateral semicircular canal. Results: Footplate thickness was smaller at the midpoint than just before the anterior crus and just after the posterior crus. Interobserver variability was lowest at the midpoint, where foot plate thickness was significantly greater in the affected ear in otosclerosis patients compared with controls (0.60 ± 0.09 mm vs 0.46 ± 0.04 mm; p < .001). Otosclerosis patients were detected using U-HRCT with a high area under the curve. Difficulty in the stapes opening procedure correlated with stapes footplate thickness. Conclusions: Footplate thickness on U-HRCT correlated with temporal bone anatomy and corresponded to surgical difficulty. Significance: U-HRCT-derived anatomic data is useful for evaluating the stapes.

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“…Secondly, distinction between medial and intimal calcification is not possible with current resolutions of CT. Intimal and medial calcification are different pathologies, with different risk factors for developing CVD 246,247 . Additionally, microcalcification (< 15 μm) cannot be assessed, as the resolution of CT is some 200 μm 222, 248,249 .…”

Section: Calcification Imaging By Computed Tomographymentioning

confidence: 99%

Key role for VSMCs in vascular remodeling and calcification

Jaminon¹

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Novel developments in non-invasive imaging of peripheral arterial disease with CT: experience with state-of-the-art, ultra-high-resolution CT and subtraction imaging

Cited by 38 publications

References 22 publications

<p>Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans</p>

<p>Quantitative Emphysema Measurement On Ultra-High-Resolution CT Scans</p>

Measurement of stapes footplate thickness in otosclerosis by ultra-high-resolution computed tomography

Key role for VSMCs in vascular remodeling and calcification

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