Novel eco-friendly acacia gum-grafted-polyamidoxime@copper ferrite nanocatalyst for synthesis of pyrazolopyridine derivatives

Hassanzadeh‐Afruzi, Fereshte; Maleki, Ali; Zare, Ehsan Nazarzadeh

doi:10.1007/s40097-022-00471-8

Cited by 10 publications

(16 citation statements)

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“…The zinc ferrite nanospheres had an average diameter of 98 nm . In FESEM images of AG- g -HPAN, swollen spherical topologies with uniform distribution throughout the smooth surface were observed . They were ascribed to cross-linking, alkaline hydrolysis, and homogeneous graft copolymerization of acrylonitrile onto the AG chain.…”

Section: Resultsmentioning

confidence: 98%

“… 46 In FESEM images of AG- g -HPAN, swollen spherical topologies with uniform distribution throughout the smooth surface were observed. 47 They were ascribed to cross-linking, alkaline hydrolysis, and homogeneous graft copolymerization of acrylonitrile onto the AG chain. The surface morphology of the AG- g -HPAN@ZnFe 2 O 4 adsorbent exhibits dispersion of zinc ferrite nanospheres inside the hydrogel matrix.…”

Section: Resultsmentioning

confidence: 99%

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Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe₂O₄ as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

et al. 2023

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The Arabic gum-grafted-hydrolyzed polyacrylonitrile/ZnFe 2 O 4 (AG-g-HPAN@ZnFe 2 O 4 ) as organic/inorganic adsorbent was obtained in three steps using grafted PAN onto Arabic gum in the presence of ZnFe 2 O 4 magnetic nanoparticles and then hydrolysis by alkaline solution. Fourier transform infrared (FT-IR), energy-dispersive X-ray analysis (EDX), field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), thermogravimetric analysis (TGA), vibrating sample magnetometer (VSM), and the Brunauer−Emmett−Teller (BET) analysis analyses were used to characterize the chemical, morphological, thermal, magnetic, and textural properties of the hydrogel nanocomposite. The obtained result demonstrated that the AG-g-HPAN@ZnFe 2 O 4 adsorbent showed acceptable thermal stability with 58% char yields and superparamagnetic property with magnetic saturation (Ms) of 24 emu g −1 . The XRD pattern showed that the semicrystalline structure with the presence of ZnFe 2 O 4 has distinct peaks which displayed that the addition of zinc ferrite nanospheres to amorphous AG-g-HPAN increased its crystallinity. The AG-g-HPAN@ZnFe 2 O 4 surface morphology exhibits uniform dispersion of zinc ferrite nanospheres throughout the smooth surface of the hydrogel matrix, and its BET surface area was measured at 6.86 m 2 /g, which was higher than that of AG-g-HPAN as a result of zinc ferrite nanosphere incorporation. The adsorption effectiveness of AG-g-HPAN@ZnFe 2 O 4 for eliminating a quinolone antibiotic (levofloxacin) from aqueous solutions was investigated. The effectiveness of adsorption was assessed under several experimental conditions, including solution pH (2−10), adsorbent dose (0.0015−0.02 g) contact duration (10−60 min), and initial concentration (50−500 mg/L). The maximum adsorption capacity (Q max ) of the produced adsorbent for levofloxacin was found to be 1428.57 mg/g (at 298 k), and the experimental adsorption data were well explained by the Freundlich isotherm model. The pseudo-second-order model satisfactorily described the adsorption kinetic data. The levofloxacin was mostly adsorbed onto the AG-g-HPAN@ZnFe 2 O 4 adsorbent via electrostatic contact and hydrogen bonding. Adsorption−desorption studies demonstrated that the adsorbent could be efficiently recovered and reused after four consecutive runs with no significant loss in adsorption performance.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe₂O₄ as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

et al. 2023

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“…8 The use of magnetic nanocatalysts in MCRs is an attractive idea for the development of sustainable methods in green synthetic chemistry. 9–11…”

Section: Introductionmentioning

confidence: 99%

“…8 The use of magnetic nanocatalysts in MCRs is an attractive idea for the development of sustainable methods in green synthetic chemistry. [9][10][11] Porous materials with outstanding properties such as, uniform pore size, adjustable porous structure, and high surface area have piqued the curiosity of scientists. 12 According to the IUPAC classication, porous materials can be categorized as microporous materials, whose pore width is less than 2 nm, mesoporous materials, whose pore width is 2-50 nm, and macroporous materials, whose pore width is more than 50 nm.…”

Section: Introductionmentioning

confidence: 99%

Facile synthesis of pyrazolopyridine pharmaceuticals under mild conditions using an algin-functionalized silica-based magnetic nanocatalyst (Alg@SBA-15/Fe₃O₄)

et al. 2023

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“…Hassanzadeh–Afruzi et al synthesized acacia gum- grafted -polyamidoxime—copper ferrite magnetic nanoparticles by graft copolymerization reaction. This ecofriendly catalyst was used for synthesis of pyrazolopyridine derivatives [ 9 ] and it was also used for repairing the damage of chlorpyrifos pesticide from contaminated water due to its superabsorbent and magnetic nature [ 10 ]. E.N.…”

Section: Introductionmentioning

confidence: 99%

Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study

Munot

Kandekar²,

Rikame³

et al. 2022

Molecules

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Thiolation of polymers is one of the most appropriate approaches to impart higher mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia was carried out by esterification with 80% thioglycolic acid. FTIR, DSC and XRD confirmed the completion of thiolation reaction. Anticancer potential of developed thiomer was studied on cervical cancer cell lines (HeLa) and more than 60% of human cervical cell lines (HeLa) were inhibited at concentration of 5 µg/100 µL. Immobilized thiol groups were found to be 0.8511 mmol/g as determined by Ellman’s method. Cytotoxicity studies on L929 fibroblast cell lines indicated thiomers were biocompatible. Bilayered tablets were prepared using Ivabradine hydrochloride as the model drug and synthesized thiolated gums as mucoadhesive polymer. Tablets prepared using thiolated polymers in combination showed more swelling, mucoadhesion and residence time as compared to unmodified gums. Thiol modification controlled the release of the drug for 24 h and enhanced permeation of the drug up to 3 fold through porcine buccal mucosa as compared to tablets with unmodified gums. Thiolated polymer showed increased mucoadhesion and permeation, anticancer potential, controlled release and thus can be utilized as a novel excipient in formulation development.

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Novel eco-friendly acacia gum-grafted-polyamidoxime@copper ferrite nanocatalyst for synthesis of pyrazolopyridine derivatives

Cited by 10 publications

References 58 publications

Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe₂O₄ as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe₂O₄ as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

Facile synthesis of pyrazolopyridine pharmaceuticals under mild conditions using an algin-functionalized silica-based magnetic nanocatalyst (Alg@SBA-15/Fe₃O₄)

Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study

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Novel eco-friendly acacia gum-grafted-polyamidoxime@copper ferrite nanocatalyst for synthesis of pyrazolopyridine derivatives

Cited by 10 publications

References 58 publications

Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe2O4 as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe2O4 as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

Facile synthesis of pyrazolopyridine pharmaceuticals under mild conditions using an algin-functionalized silica-based magnetic nanocatalyst (Alg@SBA-15/Fe3O4)

Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study

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Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe₂O₄ as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

Arabic Gum-Grafted-Hydrolyzed Polyacrylonitrile@ZnFe₂O₄ as a Magnetic Adsorbent for Remediation of Levofloxacin Antibiotic from Aqueous Solutions

Facile synthesis of pyrazolopyridine pharmaceuticals under mild conditions using an algin-functionalized silica-based magnetic nanocatalyst (Alg@SBA-15/Fe₃O₄)