Novel electrocardiographic dyssynchrony criteria improve patient selection for cardiac resynchronization therapy

Vereckei, András; Szelényi, Zsuzsanna; Kutyifa, Valentina; Zima, Endre; Szénási, Gábor; Kiss, Melinda; Katona, Gábor; Karádi, István; Merkely, Béla

doi:10.1093/europace/euw326

Cited by 18 publications

(10 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CRT plays an important role in the treatment of chronic congestive heart failure [Separham 2019;Hoosain 2017]. It can change the sequence of myocardial activation via left ventricular pacing or biventricular pacing, thereby, improving the LVEF and hemodynamic parameters [Varma 2019;Vereckei 2018]. Many methods have been developed for placing the pacing leads.…”

Section: Discussionmentioning

confidence: 99%

A Hybrid Procedure Combining Mini-Thoracotomy with Interventional Endocardial Lead Implantation for Cardiac Resynchronization Therapy in Patients with Chronic Congestive Heart Failure: A Report of Four Cases

Xiang

Gao

Yang

et al. 2020

HSF

View full text Add to dashboard Cite

Background: We describe the application and effectiveness of transthoracic electrode implantation for epicardial left ventricular pacing in cardiac resynchronization therapy (CRT) for patients with chronic congestive heart failure. Methods: We assessed four patients with chronic congestive heart failure for whom implantation of endocardial electrodes was contraindicated. The epicardial electrodes were implanted via a mini-thoracotomy in the fourth or fifth left intercostal space. We analyzed the surgical implantation technique and the short-term effectiveness of the procedure. Results: The epicardial electrodes successfully were implanted in all four patients. The patients’ hemodynamic status, cardiac function, and symptoms significantly improved. Patients I, II, III, and IV were discharged from the hospital on the 8, 11, 4, and 7 days, respectively, after the operation. Follow up lasted for 12 months. None of the patients presented with electrode fractures or surgical wound infections, and the pacing threshold and electrode impedance were normal. In one case, phrenic nerve stimulation occurred due to the low placement position of the electrode. When the electrode was moved slightly inward and upward, the sacral nerve stimulation sign disappeared, and no other complications were noted. One patient developed capsule infection, and the presence of an ectopic pacemaker was noted; therefore, a pacemaker replacement procedure was required. Conclusion: In CRT, the implantation of a left ventricular epicardial electrode through a left-sided small incision is safe, feasible, and effective. This hybrid surgery combining interventional and cardiac techniques can maximize the curative effect of CRT.

show abstract

Section: Discussionmentioning

confidence: 99%

A Hybrid Procedure Combining Mini-Thoracotomy with Interventional Endocardial Lead Implantation for Cardiac Resynchronization Therapy in Patients with Chronic Congestive Heart Failure: A Report of Four Cases

Xiang

Gao

Yang

et al. 2020

HSF

View full text Add to dashboard Cite

show abstract

“…Their marker consists of the time from onset of the QRS to the intrinsicoid deflection in V 1 , V 5 , aVL, and aVF. 4 We think that it is too early to make such strong statement based on a relatively small (124 patients) single-center study. Moreover, their method depends on subjective manual measurements.…”

Section: In Responsementioning

confidence: 99%

Response to Letter From Vereckei Regarding, “QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy”

Stipdonk

Horst

Kloosterman

et al. 2019

Circ: Arrhythmia and Electrophysiology

View full text Add to dashboard Cite

published version features the final layout of the paper including the volume, issue and page numbers. Link to publication General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research. • You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal.If the publication is distributed under the terms of Article 25fa of the Dutch Copyright Act, indicated by the "Taverne" license above, please follow below link for the End User

show abstract

“…Clinical parameters, ECG features, imaging features, and biomarkers are currently used to predict CRT response. [4][5][6] Among them, ECG is preferred as it is a more feasible test which reflects the underlying structural abnormality manifested as electrical disturbance. [6][7][8] The ECG features for CRT response majorly focus on whether strict Strauss LBBB criteria is fulfilled, as a strict LBBB morphology on surface ECG is suggested to indicate more serious in electrical disturbance rather than structural disturbance in HF.…”

Section: Introductionmentioning

confidence: 99%

Value of q waves in lateral and left precordial leads in patients with left bundle branch block to predict the response to cardiac resynchronization therapy

Zhang,

et al. 2023

Pacing Clinical Electrophis

View full text Add to dashboard Cite

BackgroundThe cardiac resynchronization therapy (CRT) non‐response rate can reach 30% in heart failure (HF) patients with left bundle branch block (LBBB). This study aimed to evaluate the value of baseline q waves in leads I, V5, or V6 in predicting response to CRT in patients with HF and LBBB.MethodsPatients with HF (left ventricular ejection fraction ≤35%) and LBBB receiving CRT implantation were retrospectively enrolled. Baseline characteristics and electrocardiogram parameters, including lateral and left precordial q waves were evaluated. Non‐response to CRT was defined as the improvement of left ventricular ejection fraction (LVEF) < 5% at a 6‐month follow‐up.ResultsA total of 132 patients (mean age 63.0 ± 10.4 years, 94 [71.2%] male) were included. Among them, 32 patients with q waves in leads I, V5, or V6 were classified into the qLBBB (+) group, and the rest without q waves in these leads were defined as the qLBBB (‐) group. The CRT non‐response rate in the qLBBB (+) group was markedly higher than that in the qLBBB (‐) group (68.8% vs. 33.3%, p < .001). Multivariable logistic regression analysis revealed that the presence of baseline q waves in leads I, V5, or V6 remained significantly associated with a higher rate of CRT non‐response in patients with HF and LBBB (odds ratio: 4.8, 95% confidence interval: 1.5–15.0, p = .007).ConclusionAny q wave in leads I, V5, or V6 was an independent predictive factor for CRT non‐response in patients with HF and LBBB.

show abstract

Novel electrocardiographic dyssynchrony criteria improve patient selection for cardiac resynchronization therapy

Abstract: The intra + interDC + TC predicts clinical response after CRT more accurately than TC alone, due to greater TA in the NICD subgroup.

Cited by 18 publications

References 21 publications

A Hybrid Procedure Combining Mini-Thoracotomy with Interventional Endocardial Lead Implantation for Cardiac Resynchronization Therapy in Patients with Chronic Congestive Heart Failure: A Report of Four Cases

A Hybrid Procedure Combining Mini-Thoracotomy with Interventional Endocardial Lead Implantation for Cardiac Resynchronization Therapy in Patients with Chronic Congestive Heart Failure: A Report of Four Cases

Response to Letter From Vereckei Regarding, “QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy”

Value of q waves in lateral and left precordial leads in patients with left bundle branch block to predict the response to cardiac resynchronization therapy

Contact Info

Product

Resources

About