Abstract:Novel thermoresponsive double‐hydrophilic fluorinated block copolymers were successfully synthesized by reversible addition‐fragmentation chain transfer (RAFT) polymerization. Poly[N‐(2,2‐difluoroethyl)acrylamide] (P2F) was synthesized via RAFT polymerization of N‐(2,2‐difluoroethyl)acrylamide (M2F) using 2 ‐dodecylsulfanylthiocarbonylsulfanyl‐2‐methylpropionic acid (DMP) as the chain transfer agent (CTA) and 2,2′‐azobisisobutyronitrile (AIBN) as the initiator. The resulting P2F macroCTA was further chain exten… Show more
“…The UCST of the PtBMA 329 -b-PVEA 142 diblock copolymer (32.0 C) is lower than that of the reference PtBMA 329 homopolymer (35.0 C), while its LCST (53.0 C) is much higher than that of the reference PVEA 133 homopolymer (40.0 C), suggesting that the solvophilic block increases the solubility of the thermo-responsive block, which is similar as discussed elsewhere. [65][66][67][73][74][75][76] The schizophrenic thermal-response of the diblock copolymer PtBMA 329 -b-PVEA 142 is reversible, and only very slight hysteresis in the cooling/ heating process is observed.…”
A doubly thermo-responsive schizophrenic diblock copolymer, poly(tert-butyl methacrylate)-block-poly[N-(4-vinylbenzyl)-N,N-diethylamine], was synthesized and its flip-flop micellization was demonstrated.
“…The UCST of the PtBMA 329 -b-PVEA 142 diblock copolymer (32.0 C) is lower than that of the reference PtBMA 329 homopolymer (35.0 C), while its LCST (53.0 C) is much higher than that of the reference PVEA 133 homopolymer (40.0 C), suggesting that the solvophilic block increases the solubility of the thermo-responsive block, which is similar as discussed elsewhere. [65][66][67][73][74][75][76] The schizophrenic thermal-response of the diblock copolymer PtBMA 329 -b-PVEA 142 is reversible, and only very slight hysteresis in the cooling/ heating process is observed.…”
A doubly thermo-responsive schizophrenic diblock copolymer, poly(tert-butyl methacrylate)-block-poly[N-(4-vinylbenzyl)-N,N-diethylamine], was synthesized and its flip-flop micellization was demonstrated.
“…Another example is stimuli‐responsive double hydrophilic block copolymers (DHBCs), particularly thermoresponsive DHBCs. They consist of a hydrophilic block and a thermoresponsive block which responds to temperature change . At conditions above the lower critical solution temperature (LCST) of the thermoresponsive block, DHBCs undergoes a coil to globular transition to form self‐assembled aggregates through temperature‐driven self‐assembly.…”
New poly(ethylene oxide)-based block copolymers (ssBCs) with a random copolymer block consisting of a reduction-responsive disulfide-labeled methacrylate (HMssEt) and a thermoresponsive di(ethylene glycol)-containing methacrylate (MEO 2 MA) units were synthesized. The ratio of HMssEt/ MEO 2 MA units in the random P(MEO 2 MA-co-HMssEt) copolymer block enables the characteristics of well-defined ssBCs to be amphiphilic or thermoresponsive and double hydrophilic. Their amphiphilicity or temperature-induced self-assembly results in nanoaggregates with hydrophobic cores having different densities of pendant disulfide linkages. The effect of disulfide crosslinking density on morphological variation of disulfide-crosslinked nanogels is investigated. In response to reductive reactions, the partial cleavage of pendant disulfide linkages in the hydrophobic cores converts the physically associated aggregates to disulfide-crosslinked nanogels. The occurrence of in-situ disulfide crosslinks provides colloidal stability upon dilution.
“…In recent years, the incorporation of fluorinated groups or sequences into functional copolymers led to the preparation of stimuli-responsive fluorinated block polymers exhibiting pH, 39,40 thermo, [41][42][43][44] and light 45 responsive features. However, reports on the synthesis and systematic investigation of the properties of fluorine containing-(co)polymers able to respond to multiple stimuli is still a challenging task.…”
The synthesis of fluorinated dual-responsive block terpolymers via sequential reversible addition-fragmentation chain transfer (RAFT) polymerization is presented. The resulting block terpolymers consist of a hydrophobic block which comprises an alternating...
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