Nuclear model calculation for cyclotron production of 61Cu as a PET imaging

Sadeghi, Mahdi; Zandi, Nadia; Bakhtiari, Mahdi

doi:10.1007/s10967-011-1557-1

Cited by 27 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More specifically, spallation reactions can be used 11 for the production of tritium or perhaps alternatively tritium can be made 12 by fusion reactions. The efficiency with which fluorine-18 can be made 13 by the [Na 23 (g,na) F 18 ] reaction has been determined. When titanium is bombarded with fast neutrons [Ti 47 (n,p)Sc 47 ] scandium-47 results 14 and cross-sections measured 15 for the reactions induced in the lighter isotope, scandium-45 by 50 MeV deuterons.…”

Section: Isotope Productionmentioning

confidence: 99%

“…Great interest is being shown in radioisotopes of copper and gallium. Positron emitting copper-61 has radiopharmaceutical potential 18 and can be prepared by the cyclotron (proton) irradiation of nickel 19 e.g., [Ni 61 (p,n)Cu 61 ], but copper-64 is more widely used. Improvements to the usual route, [Ni 64 (p,n)Cu 64 ] have been reported [20][21][22] and an alternative route, 23 [Zn 64 (n,p)Cu 64 ] investigated.…”

Section: Isotope Productionmentioning

confidence: 99%

See 1 more Smart Citation

Radiochemistry

Urch

2013

Annu. Rep. Prog. Chem., Sect. A: Inorg. Chem.

View full text Add to dashboard Cite

In this year's review of recent progress in radiochemistry, new radiochemical methods for isotope production, advances in labelling procedures, radioactive isotopes in the environment and miscellaneous topics of radiochemical interest, will be covered but not radiation chemistry, neutron activation analysis and the chemistry of elements that happen to be radioactive. HighlightsThe incorporation of radioisotopes into, sometimes onto, nanoparticles, is becoming increasingly important in nuclear medicine, for therapy and also in diagnosis (ref. 108, 109, 148, 149, 153 and 261-264). Another important piece of work was the use of density functional theory to predict the properties and behaviour of a labelled molecule (ref. 130). General introductionIt is with great sadness that the death of Michael J. Welch in May of 2012 must be recorded. He it was who brought radiochemistry to the medical world, who demonstrated, to a sceptical audience, the potential that radioactive molecules had, when combined with tomography, for diagnosis and tumour location. For forty years he ceaselessly developed nuclear medicine, extending its range to more and more positron emitting isotopes and developing new chemical ways of incorporating them into increasingly complex bio-molecules, 'radiopharmaceuticals'.No new books on radiochemistry in 2012, but a review 1 of the discovery of artificial radioactivity and the report 2 of a conference on the synthesis and applications of labelled compounds have been published. Other conferences have been more focused on specific aspects of the preparation and uses of radioactive compounds, for medical diagnosis and therapy, 3 for autoradiography 4 and to study drug metabolism. 5 A history of the use of radio-iodine has published 6 and the design of bifunctional chelating molecules, 7,8 which can both encapsulate a radioactive atom and join benignly (one hopes so) to a protein or other bio-molecule, reviewed.

show abstract