1993
DOI: 10.1099/0022-1317-74-7-1433
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Nucleotide sequence of the bovine viral diarrhoea virus Osloss strain: comparison with related viruses and identification of specific DNA probes in the 5' untranslated region

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Cited by 95 publications
(51 citation statements)
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“…As an effective vaccine has to induce protection against antigenically different virus strains it should contain conserved immunogenic epitopes. Alignment of the amino acid sequences for several CSFV (Meyers et al, 1989;Moormann et al, 1990;Mfiller, 1993) and bovine viral diarrhoea virus (BVDV) strains (Collett et al, 1988 a;De Moerlooze et al, 1993;N. Tautz, unpublished data) showed that the identified T cell epitope is highly conserved among pestiviruses.…”
Section: Discussionmentioning
confidence: 99%
“…As an effective vaccine has to induce protection against antigenically different virus strains it should contain conserved immunogenic epitopes. Alignment of the amino acid sequences for several CSFV (Meyers et al, 1989;Moormann et al, 1990;Mfiller, 1993) and bovine viral diarrhoea virus (BVDV) strains (Collett et al, 1988 a;De Moerlooze et al, 1993;N. Tautz, unpublished data) showed that the identified T cell epitope is highly conserved among pestiviruses.…”
Section: Discussionmentioning
confidence: 99%
“…The 5′ non-coding region (5′NCR) of the genome is considered to be highly conserved among pestiviruses, allowing the selection of specific primers that amplify all known pestiviruses. Therefore, the 5′NCR has been the target region when studying differences between and within pestiviruses [8,13,14,23,25]. Reverse transcriptase polymerase chain reaction (RT-PCR) has been used by various researchers for the detection of pestiviruses using oligonucleotide primers based on the 5′NCR of the viral genome [16][17].…”
Section: Introductionmentioning
confidence: 99%
“…BVDV is divided into two species based on their 5'-UTRs: BVDV-1 and -2 [55,56]. BVDV-1 strains are particularly diverse, with at least 13 genetically and antigenetically different subgroups [53,55,57,58]. Regardless of their diversity, all BVD viruses are either of the cytopathic (cp) or the non-cytopathic (ncp) biotype, based on the effect of the viral growth in cultured cells [52,53,58].…”
Section: Bovine Viral Diarrhea Virusmentioning
confidence: 99%
“…BVDV is divided into two species based on their 5'-UTRs: BVDV-1 and -2 [55,56]. BVDV-1 strains are particularly diverse, with at least 13 genetically and antigenetically different subgroups [53,55,57,58].…”
Section: Bovine Viral Diarrhea Virusmentioning
confidence: 99%