Numerical compensation of system polarization mode dispersion in polarization-sensitive optical coherence tomography

Zhang, Ellen Ziyi; Oh, Wang‐Yuhl; Villiger, Martin; Chen, Liang; Bouma, Brett E.; Vakoc, Benjamin J.

doi:10.1364/oe.21.001163

Cited by 37 publications

(29 citation statements)

References 25 publications

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“…Following the finding that polarization mode dispersion in the OCT interferometer and catheters inhibits accurate and reproducible polarimetry [107], methods were identified to mitigate this effect and enable intravascular birefringence [108,109] and depolarization [110] measurements. This work has recently been translated into clinical studies with intriguing results demonstrating the very promising utility of polarimetry for vascular and plaque characterization [37,38].…”

Section: Discussionmentioning

confidence: 99%

Intravascular optical coherence tomography [Invited]

Bouma

Villiger

Otsuka

et al. 2017

Biomed. Opt. Express

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Shortly after the first demonstration of optical coherence tomography for imaging the microstructure of the human eye, work began on developing systems and catheters suitable for intravascular imaging in order to diagnose and investigate atherosclerosis and potentially to monitor therapy. This review covers the driving considerations of the clinical application and its constraints, the major engineering milestones that enabled the current, highperformance commercial imaging systems, the key studies that laid the groundwork for image interpretation, and the clinical research that traces intravascular optical coherence tomography (OCT) from early human pilot studies to current clinical trials. Fujimoto, "Optical coherence tomography for optical biopsy. Properties and demonstration of vascular pathology," Circulation 93(6), 1206-1213 (1996). 4. D. Mozaffarian, E. Benjamin, A. Go, D. K. Arnett, M. J. Blaha, M. Cushman, S. R. Das, M. Sarah de Ferranti, J.-P. Després, and H. J. Fullerton, AHA Statistical Update: Heart Disease and Stroke Statistics (AHA, 2015). 5. E. Falk, P. K. Shah, and V. Fuster, "Coronary plaque disruption," Circulation 92(3), 657-671 (1995). 6. R. T. Lee and P. Libby, "The unstable atheroma," Arterioscler. Thromb. Vasc. Biol. 17(10), 1859-1867 (1997). 7. G. K. Sukhova, U. Schönbeck, E. Rabkin, F. J. Schoen, A. R. Poole, R. C. Billinghurst, and P. Libby, "Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques," Circulation 99(19), 2503-2509 (1999). 8. R. Virmani, F. D. Kolodgie, A. P. Burke, A. Farb, and S. M. Schwartz, "Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions," Arterioscler. Thromb. Vasc. Biol. 20(5), 1262-1275 (2000). 9. J. A. Condado, R. Waksman, O. Gurdiel, R. Espinosa, J. Gonzalez, B. Burger, G. Villoria, H. Acquatella, I. R.Crocker, K. B. Seung, and S. F. Liprie, "Long-term angiographic and clinical outcome after percutaneous transluminal coronary angioplasty and intracoronary radiation therapy in humans," Circulation 96(3), 727-732 (1997). 10. P. S. Teirstein, V. Massullo, S. Jani, J. J. Popma, G. S. Mintz, R. J. Russo, R. A. Schatz, E. M. Guarneri, S. Steuterman, N. B. Morris, M. B. Leon, and P. Tripuraneni, "Catheter-based radiotherapy to inhibit restenosis after coronary stenting," N. Engl. J. Med. 336(24), 1697-1703 (1997). 11. P. G. Yock and P. J. Fitzgerald, "Intravascular ultrasound: state of the art and future directions," Am. J. Cardiol. 81(7 7A), 27E-32E (1998). 12. P. G. Yock, P. J. Fitzgerald, D. T. Linker, and B. A. Angelsen, "Intravascular ultrasound guidance for catheterbased coronary interventions," J. Am. Coll. Cardiol. 17(6), 39-45 (1991). 13. F. M. Baer, P. Theissen, J. Crnac, M. Schmidt, M. Jochims, and H. Schicha, "MRI assessment of coronary artery disease," Rays 24(1), 46-59 (1999). 14. G. G. Zimmermann-Paul, H. H. Quick, P. Vogt, G. K. von Schulthess, D. Kling, and J. F. Debatin, "Highresolution intravascular magnetic res...

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Section: Discussionmentioning

confidence: 99%

Intravascular optical coherence tomography [Invited]

Bouma

Villiger

Otsuka

et al. 2017

Biomed. Opt. Express

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“…In fiber-based PS-OCT systems, PMD 40 in fiber and optical components, such as the circulator, are believed to contribute to the polarimetric noise in the birefringence measurement, 41,42 and approaches have been proposed to compensate for the PMD introduced by SMF and other optical components. 43 Structural properties of tissue also contribute to polarimetric noise. When light propagates in tissue, multiple scattering events can randomize the phase retardation, and scattering caused by an irregularly shaped tissue structures can introduce an abrupt change in polarization state of backscattered light.…”

Section: Discussionmentioning

confidence: 99%

Degradation in the degree of polarization in human retinal nerve fiber layer

et al. 2014

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Abstract. Using a fiber-based swept-source (SS) polarization-sensitive optical coherence tomography (PS-OCT) system, we investigate the degree of polarization (DOP) of light backscattered from the retinal nerve fiber layer (RNFL) in normal human subjects. Algorithms for processing data were developed to analyze the deviation in phase retardation and intensity of backscattered light in directions parallel and perpendicular to the nerve fiber axis (fast and slow axes of RNFL). Considering superior, inferior, and nasal quadrants, we observe the strongest degradation in the DOP with increasing RNFL depth in the temporal quadrant. Retinal ganglion cell axons in normal human subjects are known to have the smallest diameter in the temporal quadrant, and the greater degradation observed in the DOP suggests that higher polarimetric noise may be associated with neural structure in the temporal RNFL. The association between depth degradation in the DOP and RNFL structural properties may broaden the utility of PS-OCT as a functional imaging technique.

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“…Since OCT is based on broadband light covering a wide range of wavelengths, efforts have been made to mitigate effects such as polarization mode dispersion in PS-OCT systems based on optical fibers [18,[27][28][29][30].…”

Section: Brief Basics Of Octmentioning

confidence: 99%

“…Real-time display of PS-OCT data was enabled by parallel computing [115]. Computational methods were devised for removing polarization artifacts in order to produce clearer PS-OCT images [21,[27][28][29]57,116,117]. As PS-OCT is an interferometric technique based on coherent light, images are subject to speckling which sometimes obscures structural details.…”

Section: Recent Advances In Ps-oct Technologymentioning

confidence: 99%

Polarization Sensitive Optical Coherence Tomography: A Review of Technology and Applications

Baumann

2017

Applied Sciences

138

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Polarization sensitive optical coherence tomography (PS-OCT) is an imaging technique based on light scattering. PS-OCT performs rapid two-and three-dimensional imaging of transparent and translucent samples with micrometer scale resolution. PS-OCT provides image contrast based on the polarization state of backscattered light and has been applied in many biomedical fields as well as in non-medical fields. Thereby, the polarimetric approach enabled imaging with enhanced contrast compared to standard OCT and the quantitative assessment of sample polarization properties. In this article, the basic methodological principles, the state of the art of PS-OCT technologies, and important applications of the technique are reviewed in a concise yet comprehensive way.

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Numerical compensation of system polarization mode dispersion in polarization-sensitive optical coherence tomography

Cited by 37 publications

References 25 publications

Intravascular optical coherence tomography [Invited]

Intravascular optical coherence tomography [Invited]

Degradation in the degree of polarization in human retinal nerve fiber layer

Polarization Sensitive Optical Coherence Tomography: A Review of Technology and Applications

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