Cemented coal gangue-fly ash backfill (CGFB) slurry has commonly been used to control subsidence damage caused by underground coal mining. This paper discusses the characteristics of CGFB slurry fluidity in its pipe transportation. A general description about the components of the CGFB is provided involving the percentage of composition, particle size distribution (PSD) and rheological performance. The CGFB flow characteristics of the slurry pipeline were simulated in a straight pipe and 90° elbow pipe, respectively, combined with the pressure loss and conveying velocity distribution. With the help of the commercial computational fluid dynamic (CFD) code FLUENT, the modeling was conducted with various slurry feeding velocities. These results showed the local resistance loss in a bending pipe is significantly higher than the resistance in a straight pipe under the same conditions associated with CGFB transportation. The velocity distribution of the slurry solid particles in the slurry’s movement forward is more decentralized as the hydraulic inlet velocity increases. Based on these simulation data, a correlation was developed to predict the resistance loss of the CGFB slurry as a function of the hydraulic inlet velocity, pipe diameter and CGFB slurry rheological characteristics.