Background People with dementia are regularly hospitalized. Person-centered care is the preferred model for caring for people with dementia. To improve the quality of care for people with dementia in an acute care setting, knowledge of the level of person-centeredness of the care is relevant. The POPAC is a tool to determine the level of Person-centred care. Translation enables international comparisons of data and outcomes of Person-centred care. This study aimed to translate and cross-nationally validate the Dutch Person-centred care of Older People with cognitive impairment in Acute Care scale and to evaluate its psychometric properties. Methods After translation, a total of 159 nurses recruited from six hospitals and via social media completed the POPAC. A confirmatory factor analysis was performed to test the factor-structure, and a Cronbach’s alpha scale was utilized to establish the reliability of the scale. Results A confirmatory factor analysis showed that the fit by the Confirmatory Fit Index was a nearly acceptable model fit. The Root Mean Square Error of Approximation and the Standardized Root Mean Square Residual suggested an acceptable model fit. The findings of the authors confirm a three-dimensional structure suggested by previous research. The loadings of the items indicate that these are strong associations with each of the factors. Besides, the factor correlations also indicate that these are strongly associated. These findings indicate that the factors are strongly associated with a general POPAC factor. This study confirms that, statistically, Item 5 could be deleted to improve the reliability of the instrument. Instead of deleting this item, the authors suggest considering rephrasing it into a positive item. Conclusions The Dutch version of the POPAC is sufficiently valid and reliable and can be utilized for assessing person-centered care in acute care hospitals. The study enables nurses to interpret and compare levels of Person-centred care in wards and hospital levels between regions and countries. The results form an important basis for improving the quality of care and nurse-sensitive outcomes such as prevention of complications and length of hospital stay.