Nutrient Status Assessment in Individuals and Populations for Healthy Aging—Statement from an Expert Workshop

Mathers, John C.; Feskens, Edith J. M.; Schols, A.M.W.J.; Navis, Gerarda; Kuipers, Folkert; Weber, Peter; Eggersdorfer, Manfred

doi:10.3390/nu7125547

Cited by 28 publications

(15 citation statements)

References 36 publications

(34 reference statements)

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“…The University Medical Center Groningen (UMCG) in The Netherlands organizes annual symposia within the compass of medicine and nutrition, as part of its Healthy Ageing program. Previously published proceedings of these symposia have examined the relationship of nutrients with lifelong health and disease [ 1 ], with healthy aging [ 2 ], with malnutrition and obesity [ 3 ], and with nutrient–drug interactions [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

The role of the microbiome for human health: from basic science to clinical applications

et al. 2018

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The 2017 annual symposium organized by the University Medical Center Groningen in The Netherlands focused on the role of the gut microbiome in human health and disease. Experts from academia and industry examined interactions of prebiotics, probiotics, or vitamins with the gut microbiome in health and disease, the development of the microbiome in early-life and the role of the microbiome on the gut–brain axis. The gut microbiota changes dramatically during pregnancy and intrinsic factors (such as stress), in addition to extrinsic factors (such as diet, and drugs) influence the composition and activity of the gut microbiome throughout life. Microbial metabolites, e.g. short-chain fatty acids affect gut–brain signaling and the immune response. The gut microbiota has a regulatory role on anxiety, mood, cognition and pain which is exerted via the gut–brain axis. Ingestion of prebiotics or probiotics has been used to treat a range of conditions including constipation, allergic reactions and infections in infancy, and IBS. Fecal microbiota transplantation (FMT) highly effective for treating recurrent Clostridium difficile infections. The gut microbiome affects virtually all aspects of human health, but the degree of scientific evidence, the models and technologies and the understanding of mechanisms of action vary considerably from one benefit area to the other. For a clinical practice to be broadly accepted, the mode of action, the therapeutic window, and potential side effects need to thoroughly be investigated. This calls for further coordinated state-of-the art research to better understand and document the human gut microbiome’s effects on human health.

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Section: Introductionmentioning

confidence: 99%

The role of the microbiome for human health: from basic science to clinical applications

et al. 2018

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“…Health and longevity are the eternal pursuit of human beings. Diet is an important factor affecting health and longevity [ 1 , 2 ]. Appropriate dietary alterations, such as dietary restriction, can promote health and increase the life span of laboratory model organisms [ 3 ], but malnutrition, nutritional excess or imbalance accelerates the aging process and causes a variety of geriatric diseases in humans [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Nutrient Intake Is Associated with Longevity Characterization by Metabolites and Element Profiles of Healthy Centenarians

Cai

Zhao

et al. 2016

Nutrients

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The relationships between diet and metabolites as well as element profiles in healthy centenarians are important but remain inconclusive. Therefore, to test the interesting hypothesis that there would be distinctive features of metabolites and element profiles in healthy centenarians, and that these would be associated with nutrient intake; the short chain fatty acids (SCFAs), total bile acids and ammonia in feces, phenol, p-cresol, uric acid, urea, creatinine and ammonia in urine, and element profiles in fingernails were determined in 90 healthy elderly people, including centenarians from Bama county (China)—a famous longevous region—and elderly people aged 80–99 from the longevous region and a non-longevous region. The partial least squares-discriminant analysis was used for pattern recognition. As a result, the centenarians showed a distinct metabolic pattern. Seven characteristic components closely related to the centenarians were identified, including acetic acid, total SCFA, Mn, Co, propionic acid, butyric acid and valeric acid. Their concentrations were significantly higher in the centenarians group (p < 0.05). Additionally, the dietary fiber intake was positively associated with butyric acid contents in feces (r = 0.896, p < 0.01), and negatively associated with phenol in urine (r = −0.326, p < 0.01). The results suggest that the specific metabolic pattern of centenarians may have an important and positive influence on the formation of the longevity phenomenon. Elevated dietary fiber intake should be a path toward health and longevity.

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“…Thus, according to the norms of fiber consumption, 14 g of fiber is necessary for every 1,000 calories [20]. A daily need for DF is: 19…25 g for children from 1 to 8 years, 31…38 g for men, and 26…25 g for women [21].…”

Section: Literature Review and Problem Statementmentioning

confidence: 99%

Research of recipe components influence on the properties of dairy-protein mashes for semi-finished products

Грек

Tymchuk

Tsygankov

et al. 2019

EEJET

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Technology and equipment of food production 41 of products in terms of the content of dietary fiber, micro-and macronutrients, vitamins, proteins, and other nutrients. A search for new functional and technological ingredients made of available raw materials, development of technologies for products with such additives and studying of their consumer properties are urgent tasks for the dairy industry. 1. Introduction One of the ways to improve properties of product structure and food diets in general is introduction of specially treated vegetable raw materials. The approach makes it possible to correct consistency directly and to balance a chemical composition

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Nutrient Status Assessment in Individuals and Populations for Healthy Aging—Statement from an Expert Workshop

Cited by 28 publications

References 36 publications

The role of the microbiome for human health: from basic science to clinical applications

The role of the microbiome for human health: from basic science to clinical applications

Nutrient Intake Is Associated with Longevity Characterization by Metabolites and Element Profiles of Healthy Centenarians

Research of recipe components influence on the properties of dairy-protein mashes for semi-finished products

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