Nutrition assessment in patients undergoing liver transplant

Bakshi, Neha; Singh, Kuldeep

doi:10.4103/0972-5229.142177

Cited by 21 publications

(13 citation statements)

References 60 publications

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“…Combination of different nutrition tools like anthropometry, and body composition analysis, have been reported to formulate a composite score for malnutrition assessment [57]. The goals of nutritional therapy are mainly focused on improving protein malnutrition and regulate nutrient deficiencies.…”

Section: Nutritional Support By Nutraceuticals and Functional Foods Omentioning

confidence: 99%

Current Knowledge about the Effect of Nutritional Status, Supplemented Nutrition Diet, and Gut Microbiota on Hepatic Ischemia-Reperfusion and Regeneration in Liver Surgery

et al. 2020

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Ischemia-reperfusion (I/R) injury is an unresolved problem in liver resection and transplantation. The preexisting nutritional status related to the gut microbial profile might contribute to primary non-function after surgery. Clinical studies evaluating artificial nutrition in liver resection are limited. The optimal nutritional regimen to support regeneration has not yet been exactly defined. However, overnutrition and specific diet factors are crucial for the nonalcoholic or nonalcoholic steatohepatitis liver diseases. Gut-derived microbial products and the activation of innate immunity system and inflammatory response, leading to exacerbation of I/R injury or impaired regeneration after resection. This review summarizes the role of starvation, supplemented nutrition diet, nutritional status, and alterations in microbiota on hepatic I/R and regeneration. We discuss the most updated effects of nutritional interventions, their ability to alter microbiota, some of the controversies, and the suitability of these interventions as potential therapeutic strategies in hepatic resection and transplantation, overall highlighting the relevance of considering the extended criteria liver grafts in the translational liver surgery.

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Section: Nutritional Support By Nutraceuticals and Functional Foods Omentioning

confidence: 99%

Current Knowledge about the Effect of Nutritional Status, Supplemented Nutrition Diet, and Gut Microbiota on Hepatic Ischemia-Reperfusion and Regeneration in Liver Surgery

et al. 2020

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“…This study included 50 healthy volunteers; 30(60%) males and 20(40%) females, with mean age 50.32+9.43. As shown in table (8) there is a highly significant difference regarding MAC, TSFT and HGS between the control group and the patients group. PEM is a common complication among patients with liver cirrhosis that ranges from about 20% in compensated liver disease to 65%-100% in decompensated liver cirrhosis.…”

Section: Characteristics Of the Control Group:-mentioning

confidence: 89%

Hand Grip Strength as a Nutritional Assessment Tool in Patients With Liver Cirrhosis.

Elkholy¹,

Mogawer²,

Mansour³

et al. 2016

IJAR

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Liver cirrhosisnutrition-hand grip strength. Background:-Protein energy malnutrition (PEM) is a recognized complication in patients with liver cirrhosis; most randomized studies have shown a significant increase in morbidity and mortality in relation to its severity. Yet, there is no gold standard method for nutritional assessment of these patients up till now. Aim of the work:-the aim of this study is to assess the efficacy of hand grip strength as a nutritional assessment tool and its sensitivity and specificity in detecting PEM. Methods:-This is a case control study that was designed to analyze data from 78 Egyptian patients with CHILD C liver cirrhosis. Subjective global assessment (SGA), anthropometric tools, hand grip strength (HGS) were used to assess the nutritional status of these patients. It also included 50 healthy volunteers with matched age, gender and area of residence. Results:-Severe PEM was prevalent among the patients; HGS was highly correlated to the degree of malnutrition (p-value = 0.008). ROC curve analysis showed a criterion of 17.6 with specificity 90% and sensitivity of 60 %. Conclusion:-PEM is prevalent among patients with cirrhosis. Nutritional assessment in decompensated patients remains a challenge for clinicians. HGS is a simple, bed side tool that can be used to assess the muscle status and can be used in a complementary manner with other methods for proper assessment of the patients.

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“…Various previous studies have focused on the need for nutrition intervention in LT recipients because of the high prevalence of malnutrition and nutrition-related complication (hypermetabolism, gastrointestinal symptoms, etc.) before and after the LT.[21011] The present study attempted to record these much-needed data on nutrition requirements and nutrition progression. The study could include only 54 LT patients.…”

Section: Discussionmentioning

confidence: 99%

“…Various studies have focused on nutrition assessment and malnutrition in pre-LT phase and its effect on various prognostic, nutritional, and clinical factors and the outcomes of the surgery. [11121314151617] There are very few studies addressing the nutritional aspects of acute post-LT phase. After LT, there is altered metabolism as the protein catabolism increases because of higher nitrogen losses.…”

Section: Introductionmentioning

confidence: 99%

Nutrition management of acute postliver transplant recipients

Bakshi¹,

Singh²

2018

Indian Journal of Critical Care Medicine

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Aim:Acute post liver transplant (LT) phase is characterized by hypermetabolism and increased nutrient requirements. This study aimed to provide the cardinal data on nutrition progression in the management of acute post-LT patients.Methods:This exploratory study recruited 54 adult acute post-LT recipients. The information regarding patient stay, weight status, biochemical parameters, and route of feeding was gathered. Recipients' dietary and nutrient intake was computed by 24-h dietary recall method.Results:The data exhibited a significant trend of lower hemoglobin, platelet, and albumin levels and increased bilirubin (T), alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transferase levels (P < 0.05). In acute post-LT patients, a significant decrease in weight status (P < 0.001*) was observed. The recipients' information on daily nutrition progression showed significantly lower intake of calorie, protein, fats, calcium (P < 0.05) and lower percentage adequacy of other nutrients as compared to the recommended guidelines. The energy and protein intake from the parenteral route of feeding significantly decreased and that of through oral route significantly increased (P < 0.05) from postoperative day (POD) 2 to POD 9 and POD 12.Conclusion:There are scant data on nutrition management in acute post-LT phase. The present study provides the framework for the formulation of continuous, patient-centric, aggressive nutrition management interventions for acute post-LT recipients.

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Nutrition assessment in patients undergoing liver transplant

Cited by 21 publications

References 60 publications

Current Knowledge about the Effect of Nutritional Status, Supplemented Nutrition Diet, and Gut Microbiota on Hepatic Ischemia-Reperfusion and Regeneration in Liver Surgery

Current Knowledge about the Effect of Nutritional Status, Supplemented Nutrition Diet, and Gut Microbiota on Hepatic Ischemia-Reperfusion and Regeneration in Liver Surgery

Hand Grip Strength as a Nutritional Assessment Tool in Patients With Liver Cirrhosis.

Nutrition management of acute postliver transplant recipients

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