Nutritional and Biochemical Investigations on Disaccharide Alcohols

Grupp, Uta; Siebert, Günther; Gerlach, Heike; Zehner, Albrecht

doi:10.1159/000176111

Ann Nutr Metab

1977

DOI: 10.1159/000176111

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Nutritional and Biochemical Investigations on Disaccharide Alcohols

Uta Grupp¹,

Günther Siebert²,

Heike Gerlach³

et al.

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1978

1981

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Cited by 2 publications

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References 7 publications

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“…The present study is in consequence concerned with the digestibility of hydrogenated palatinose and the energetic utilisation of its cleavage products in the metabolism of man and rat. Several short communications have appeared since this work was started [22,40,52,53].…”

mentioning

confidence: 99%

Metabolism of hydrogenated palatinose, an equimolar mixture ofα-D-glucopyranosido-1,6-sorbitol andα-D-glucopyranosido-1,6-mannitol

Grupp

Siebert

1978

Res. Exp. Med.

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Hydrogenated palatinose, an equimolar mixture of alpha-D-glucopyranosido-1,6-sorbitol and alpha-D-glucopyranosido-1,6-mannitol, was investigated as a potential oral sugar substitute in the following experiments in man and rat. 1. Enzymatic cleavage occurred at slow rates by maltase (alpha-glucosidase) of jejunal mucosa, liver lysosomes and yeast. 2. Part of ingested hydrogenated palatinose arrived unsplit at the caecum of the rat and underwent fermentation there; excretion in feces and urine are neglegible in man and rat. 3. Growth and maintenance of rats demonstrated 20--40 percent diminished caloric utilisation of diets containing 34.5 percent hydrogenated palatinose whereas indirect calorimetry in man showed about 50 percent caloric deficit. 4. Blood sugar did not increase in man after oral doses up to 100 g. 5. The capacity of the rat kidneys for excretion of hydrogenated palatinose and its constituents was high, symptoms of incompatibility were not observed.

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mentioning

confidence: 99%

Metabolism of hydrogenated palatinose, an equimolar mixture ofα-D-glucopyranosido-1,6-sorbitol andα-D-glucopyranosido-1,6-mannitol

Grupp

Siebert

1978

Res. Exp. Med.

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Extended zigzag conformation of 1-O-d-ga-glucopyranosyl-d-mannitol

Lindner

Lichtenthaler

1981

Carbohydrate Research

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Nutritional and Biochemical Investigations on Disaccharide Alcohols

Cited by 2 publications

References 7 publications

Metabolism of hydrogenated palatinose, an equimolar mixture ofα-D-glucopyranosido-1,6-sorbitol andα-D-glucopyranosido-1,6-mannitol

Metabolism of hydrogenated palatinose, an equimolar mixture ofα-D-glucopyranosido-1,6-sorbitol andα-D-glucopyranosido-1,6-mannitol

Extended zigzag conformation of 1-O-d-ga-glucopyranosyl-d-mannitol

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