2020
DOI: 10.7759/cureus.8459
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Objective Characterization of Opiate-Induced Chest Wall Rigidity

Abstract: Introduction Opiate-induced chest wall rigidity is a syndrome that largely goes unrecognized. To date, no study has presented significant objective data to better understand this syndrome. Objective The aim of this study was to explore the correlation between the dosage of opiates and the incidence of chest wall rigidity, ventilatory changes, and effects of naloxone administration. Methods A total of eight patients were identified as having episodes of chest wall rigidity, with half of the population being fem… Show more

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Cited by 7 publications
(6 citation statements)
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“…In 2018, Trujillo and colleagues reviewed cases from 2014 to 2017 at a level 2 trauma center and objectively described ventilator parameters and opioid dosage. Of the eight cases they reviewed, it seems likely that many more cases went undiagnosed and that WCS is an underdiagnosed complication of opiates [ 6 ]. This is supported by evidence from Kinshella et al who investigated overdoses at a Canadian-supervised injection site and described typical and atypical overdose presentations [ 7 ].…”
Section: Discussionmentioning
confidence: 99%
“…In 2018, Trujillo and colleagues reviewed cases from 2014 to 2017 at a level 2 trauma center and objectively described ventilator parameters and opioid dosage. Of the eight cases they reviewed, it seems likely that many more cases went undiagnosed and that WCS is an underdiagnosed complication of opiates [ 6 ]. This is supported by evidence from Kinshella et al who investigated overdoses at a Canadian-supervised injection site and described typical and atypical overdose presentations [ 7 ].…”
Section: Discussionmentioning
confidence: 99%
“…Multi-mode analgesia is the combined application of various methods to reduce the dose of opioids and their adverse reactions. As the main drug for postoperative analgesia, opioids are prone to cause intestinal paralysis, PONV, and other complications, and reducing their dose is conducive to the early recovery of patients [9][10][11][12]. Burnstock [13,14] proposed the original hypothesis that acupuncture increases endogenous opioid analgesia and provided evidence for the involvement of purine receptors in acupuncture analgesia.…”
Section: Reduction Of Perioperative Painmentioning
confidence: 99%
“…The incidence has been estimated anywhere between 8% and 100% 16 . A fairly recent review suggests that it may be an even more significant contributor to death than previously thought, 16 and a clear treatment paradigm has not yet been developed 17 . Carfentanil has an even higher potency than fentanyl 12 and is relatively easy to make.…”
Section: Commentmentioning
confidence: 99%