Observations on LABORATORY AND HOSPITAL INFECTIONS WITH YELLOW FEVER IN ENGLAND

Low, George C.; Fairley, N. Hamilton

doi:10.1136/bmj.1.3655.125

Cited by 21 publications

(5 citation statements)

References 2 publications

(4 reference statements)

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“…Except for one case of nosocomial transmission in the 1930s 38 , there are no reports of direct human-to-human YFV transmission outside the laboratory (see Biosafety below). However, transplacental- 39 , 40 , breastfeeding- 41 – 43 , and blood donation-based viral transmission 44 has been described for the live attenuated YFV vaccines.…”

Section: Epidemiology and Geographical Spreadmentioning

confidence: 99%

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Yellow fever in the diagnostics laboratory

Domingo

Charrel

Schmidt‐Chanasit

et al. 2018

Emerging Microbes & Infections

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Yellow fever (YF) remains a public health issue in endemic areas despite the availability of a safe and effective vaccine. In 2015–2016, urban outbreaks of YF were declared in Angola and the Democratic Republic of Congo, and a sylvatic outbreak has been ongoing in Brazil since December 2016. Of great concern is the risk of urban transmission cycles taking hold in Brazil and the possible spread to countries with susceptible populations and competent vectors. Vaccination remains the cornerstone of an outbreak response, but a low vaccine stockpile has forced a sparing-dose strategy, which has thus far been implemented in affected African countries and now in Brazil. Accurate laboratory confirmation of cases is critical for efficient outbreak control. A dearth of validated commercial assays for YF, however, and the shortcomings of serological methods make it challenging to implement YF diagnostics outside of reference laboratories. We examine the advantages and drawbacks of existing assays to identify the barriers to timely and efficient laboratory diagnosis. We stress the need to develop new diagnostic tools to meet current challenges in the fight against YF.

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Section: Epidemiology and Geographical Spreadmentioning

confidence: 99%

“…Over 40 instances of professionally acquired YFV infections were reported in the pre-vaccine era. These cases included a physician caring for a patient, laboratory staff handling biological samples from infected patients or laboratory animals, and one case of transmission from the bite of an infected mosquito 38 , 104 – 107 .…”

Section: Biosafetymentioning

confidence: 99%

Yellow fever in the diagnostics laboratory

Domingo

Charrel

Schmidt‐Chanasit

et al. 2018

Emerging Microbes & Infections

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show abstract

“…The exact circum stances under which they became infected are not known, although Young may have been infected during the autopsy on Noguchi (119). Three others who died during this brief period were an investigator in Brazil who handled blood from an infected monkey (11,16), an entomologist bitten by an infective mosquito in Nigeria (11), and a technician in London who per formed a blood count on a yellow fever patient (73,93). The most recent case was the young professor, Cuervo, who in 1942 contracted the disease while preparing yellow fever vaccine in Colombia (66).…”

Section: Viral Infectionsmentioning

confidence: 99%

Laboratory-Associated Infections: Incidence, Fatalities, Causes, and Prevention

Pike¹

1979

Annu. Rev. Microbiol.

205

113

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“…Routes of transmission include percutaneous, mucous membrane, bone marrow transplant, organ transplant, hemodialysis, and transfusion of blood products (6)(7)(8)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) (Table) However, despite good evidence for its transmission in healthcare settings, dengue is currently not considered a risk to blood safety.…”

mentioning

confidence: 99%