history of spina bifida cystica and cranium bifidum cysticum: the major central nervous system malformations in South Wales. Part IV. The 425 cases of spina bifida cystica and cranium bifidum cysticum born in a population of 850,000 between 1956 and 1962 (with an incidence of 4-12 per 1000 births) were followed. Most did not receive the modern treatment for the condition. Follow-up in 1968 showed that 25% were stillborn, 13% died during the first week of perinatal causes, a further 47 % died mostly of the complications of the condition, and 15% are still alive. Life