Occupation, Lifestyle, Diet, and Invasive Fungal Infections

Sipsas, Nikolaos V.; Kontoyiannis, Dimitrios P.

doi:10.1007/s15010-008-8129-5

Cited by 51 publications

(50 citation statements)

References 120 publications

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“…Estudos indicam que micoses sistêmicas e subcutâneas são as principais causas de morbidade e mortalidade em pessoas imunossuprimidas (Sipsas & Kontoyiannis 2008).…”

Section: Discussionunclassified

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Doenças micóticas em gatos no Rio Grande do Sul

et al. 2017

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RESUMO.-As enfermidades fúngicas são diagnósticos diferenciais de diversas morbidades de caráter infeccioso, degenerativo ou proliferativo neoplásico, principalmente em gatos, que é a espécie mais suscetível a estas. Este trabalho descreve os achados anatomopatológicos de doenças fúngi-cas em gatos no período de janeiro de 2005 a dezembro de 2015 pelo SPV-UFRGS. Foram revisados 1.274 protocolos de necropsia e encontrou-se 17 casos de micoses, correspondendo a 1,33% dos diagnósticos. Quanto às amostras provenientes de biopsias, foram verificados 2.615 protocolos e detectou-se 59 casos de doenças fúngicas, totalizando 2,25% dos diagnósticos, sendo revisados seus achados macroscópi-cos, microscópicos, colorações especiais e cultivo micológico. O principal diagnóstico encontrado foi esporotricose com 34 casos de biópsia e cinco de necropsia. Criptococose obteve seis diagnósticos na necropsia e 13 na biópsia. O pseudomicetoma dermatofítico possui cinco casos de biópsia e dois de necropsia. Histoplasmose obteve um diagnóstico na necropsia e dois na biópsia. Aspergilose teve dois casos diagnosticados na necropsia. Candidíase e feo-hifomicose obtiveram um caso cada. Em quatro ocasiões, não se pode identificar o agente envolvido na lesão e foram classificados conforme a alteração morfológica em: dermatite fúngica, enterite fúngi-ca, rinite micótica e dermatite e osteomielite fúngica. Através deste trabalho, pode-se identificar que a esporotricose foi o diagnóstico de doença fúngica mais frequente em felinos, seguido da criptococose e pseudomicetoma dermatofítico.

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“…Estudos indicam que micoses sistêmicas e subcutâneas são as principais causas de morbidade e mortalidade em pessoas imunossuprimidas (Sipsas & Kontoyiannis 2008).…”

Section: Discussionunclassified

“…Estima-se que animais de companhia possam transmitir de 30 a 40 doenças zoonóticas (Moriello 2003) e que as infecções fúngicas sistêmicas sejam as principais causas de morbidade e mortalidade em pessoas imunodeprimidas (Sipsas & Kontoyiannis 2008).…”

Section: Introductionunclassified

Doenças micóticas em gatos no Rio Grande do Sul

et al. 2017

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“…12 High risk jobs included those employments more likely to expose the patient to fungal spores, such as construction work, farming, gardening, being a florist shop employee, and forestry work. 13 High risk hobbies included those activities that were more likely to expose the participants to fungal spores, such as hunting, gardening, fishing, and hiking. 13 Being overweight was defined as having a body mass index ≥30 kg/m 2 .…”

Section: Definitionsmentioning

confidence: 99%

“…13 High risk hobbies included those activities that were more likely to expose the participants to fungal spores, such as hunting, gardening, fishing, and hiking. 13 Being overweight was defined as having a body mass index ≥30 kg/m 2 . 14 Patients with proven/probable mold infections were termed "mold cases".…”

Section: Definitionsmentioning

confidence: 99%

Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM 2010-a multicenter study)

Caira

Candoni²,

Verga

et al. 2015

Haematologica

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Correct definition of the level of risk of invasive fungal infections is the first step in improving the targeting of preventive strategies. We investigated the potential relationship between pre-hospitalization exposure to sources of fungi and the development of invasive fungal infections in adult patients with newly diagnosed acute myeloid leukemia after their first course of chemotherapy. From January 2010 to April 2012, all consecutive acute myeloid leukemia patients in 33 Italian centers were prospectively registered. Upon first admission, information about possible pre-chemotherapy risk factors and environmental exposure was collected. We recorded data regarding comorbid conditions, employment, hygienic habits, working and living environment, personal habits, hobbies, and pets. All invasive fungal infections occurring within 30 days after the first course of chemotherapy were recorded. Of the 1,192 patients enrolled in this study, 881 received intensive chemotherapy and were included in the present analysis. Of these, 214 developed an invasive fungal infection, including 77 proven/probable cases (8.7%). Of these 77 cases, 54 were proven/probable invasive mold infections (6.1%) and 23 were proven yeast infections (2.6%). Upon univariate analysis, a significant association was found between invasive mold infections and age, performance status, diabetes, chronic obstructive pulmonary disease, smoking, cocaine use, job, hobbies, and a recent house renovation. Higher body weight resulted in a reduced risk of invasive mold infections. Multivariate analysis confirmed the role of performance status, job, body weight, chronic obstructive pulmonary disease, and house renovation. In conclusion, several hospital-independent variables could potentially influence the onset of invasive mold infections in patients with acute myeloid leukemia. Investigation of these factors upon first admission may help to define a patient's risk category and improve targeted prophylactic strategies. (Clinicaltrial.gov: NCT01315925) Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM

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“…Many outdoor activities such as gardening, hunting, or camping, and few sports such as caving or cave diving, are associated with increased environmental exposure to pathogenic fungi and increased risk of invasive fungal diseases (IFDs) (Sipsas & Kontoyiannis, 2008). Inhalation of conidia and direct inoculation through minor skin lesions are the most common mechanisms for developing fungal disease.…”

Section: Air Quality and Fungal Infections 41 Hospital Indoor Air Qumentioning

confidence: 99%