2022
DOI: 10.1111/resp.14272
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Occupational COPD—The most under‐recognized occupational lung disease?

Abstract: Chronic obstructive pulmonary disease (COPD) is caused by exposure to noxious particles and gases. Smoking is the main risk factor, but other factors are also associated with COPD. Occupational exposure to vapours, gases, dusts and fumes contributes to the development and progression of COPD, accounting for a population attributable fraction of 14%. Workplace pollutants, in particular inorganic dust, can initiate airway damage and inflammation, which are the hallmarks of COPD pathogenesis. Occupational COPD is… Show more

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Cited by 65 publications
(44 citation statements)
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“…COPD is a complex and heterogeneous disease. Exposure to noxious particles/gases and predisposing genetic factors plays a potential role in the pathogenesis of COPD [ 1 , 35 ]. Cigarette smoke, the most representative noxious particle activates inflammatory chemokines and cytokines in the small airways, directly causing damage to airway epithelium.…”
Section: Discussionmentioning
confidence: 99%
“…COPD is a complex and heterogeneous disease. Exposure to noxious particles/gases and predisposing genetic factors plays a potential role in the pathogenesis of COPD [ 1 , 35 ]. Cigarette smoke, the most representative noxious particle activates inflammatory chemokines and cytokines in the small airways, directly causing damage to airway epithelium.…”
Section: Discussionmentioning
confidence: 99%
“…Asthma and COPD have multifactorial causes and are associated with exposure factors related to the occupational or home environment (tobacco and wood smoke), unfavorable socioeconomic status, and genetic factors [7][8][9][10] . According to the literature, air polluting agents are related to lung diseases and respiratory symptoms 11 .…”
Section: Introductionmentioning
confidence: 99%
“… 4 The prevalence of COPD differs between countries, reflecting the diverse age composition of the population, genetic predispositions, healthcare resources, and various exposure to risk factors. 5 The prevalence of COPD is almost 4% of the global population. 6 Prevalence rises to 10% among people aged 40 and older.…”
Section: Introductionmentioning
confidence: 99%