Occurence and Antimicrobial Resistant Patterns of Methicillin Resistant Staphylococcus Aureus (MRSA) Among Practicing Veterinarians in Kebbi State, Nigeria

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is an emerging zoonotic pathogen incriminated in causing multiple disease conditions in humans and livestock. Studies have shown relationships between livestock rearing and increased MRSA colonization risk among farm workers, and also suggest that livestock may serves as reservoirs of the bacteria and could also infect humans via close contact and consumption of contaminated animal products. The aim of this study was to investigate if practicing veterinarians with significant livestock contacts are at risk for MRSA colonization. Therefore, a non-randomized survey was conducted to establish the presence of MRSA among veterinarians practicing in Kebbi State Nigeria, using both cultural characteristics and molecular detection of the resistant gene (mecA). Forty-one (41) nasal swabs were aseptically collected. The detection rate of MRSA in the veterinarians was 14.6 %. The study revealed a high occurrence rate of MRSA among veterinarians in the study area. The relatively high prevalence recorded among veterinarians in this study could be attributed to the poor understanding of MRSA as a disease, its mode of transmission and its status in the country which have contributed immensely to the little/no awareness of MRSA among veterinarians and hence making it favourable for the bacteria (MRSA) to spread.

Current Trends of Resistance Among Gram Negative and Gram Positive Bacteria Isolated from Tertiary Care Hospital

“…The findings of the current study revealed a serious problem with the increasing antimicrobial resistance rate among the bacterial isolates from the hospitalacquired infections, comparable to the worldwide 17,18 trends. In our study, Gram-negative bacteria showed extreme resistance against co-trimoxazole.…”

Occurrence and Antibiotic Resistance Profiles of Methicillin-Resistant Staphylococcus Aureus (Mrsa) in Layer Chickens in Kebbi, Nigeria

“…The result showed a high resistance to penicillin, oxytetracycline, neomycin, erythromycin, gentamicin, and sulfonamides. Reports from A n u e y i a g u and I s i y a k u [1], J a h a n et al [16] and G a d d a f i et al [12] in agreement showed a remarkably high MRSA resistance to penicillin because it is the drug of choice in S. aureus infection. High resistance to oxytetracycline noticed in this study could be attributed to the assertion by O l a t o y e [27] who opinioned that tetracycline is commonly used as a feed additive and for prophylaxis in animal production in Nigeria.…”

Evidence of Methicillin Resistant Staphylococcus Aureus (MRSA) in Pet and Stray Dogs Within Sokoto Metropolis, Nigeria

“…The current study's PCR investigation indicated the presence of the mecA gene at 163 bp in 15 of the 20 isolates that were phenotypically MRSA positive. When it comes to MRSA detection and characterization, the pres-ence of the mecA gene is the gold standard [11]. According to studies, the existence of the mecA gene in animals and animal products supports this claim [12,27,37].…”

“…MRSA strains carry a diverse and transmissible genetic element designated as MRSA colonization in dogs which have been extensively studied in most parts of the world with varying prevalence rates of 0-6 % [23]. However, despite reports of the pathogen in humans [11] and the unethical use of antibiotics by veterinary quacks and animal owners, there is very little information about the presence of MRSA in dogs in Nigeria.…”