Of Stents and Scaffolds

Ormiston, John A.; Webster, Mark

doi:10.1161/circinterventions.116.004249

Cited by 3 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Based on the obtained knowledge, various stent structures were 3D printed to verify the effectiveness of the proposed 3D printing system. Herein, three typical stents including BVS1.1, Palmaz‐Schatz, and ART18Z were selected and the schematics are illustrated in Fig. a‐1, b‐1, and c‐1, respectively.…”

Section: Resultsmentioning

confidence: 99%

Experimental study of polymeric stent fabrication using homemade 3D printing system

Zhao

Zhou

Sun³

et al. 2019

Polymer Engineering & Sci

View full text Add to dashboard Cite

Biodegradable polymeric stents have received extensive attention due to the high efficiency in interventional therapy. Fabrication of well-defined polymeric stents still poses a significant fabrication challenge. This study aims to investigate the feasibility of using a homemade three-dimensional (3D) printing system to directly print customized polymeric stents. In the proposed system, a rotating shaft with controllable temperature and rotating speed has been integrated into a fused deposition modeling-based 3D printing system to support the printed stents stably in situ. In addition, the effects of operating conditions including the rotating speed, printing temperature, printing speed, and step distance on the dimensions of the 3D printed stents have been investigated. Furthermore, orthogonal experiments have been designed and performed to comprehensively explore the significance of each processing parameter. Finally, based on the obtained knowledge, polymeric stents with various structures have been successfully 3D printed using the homemade 3D printing system with relatively high shape fidelity. FIG. 7. Evaluation of the effects of operating conditions on the 3D printed stents. [Color figure can be viewed at wileyonlinelibrary.com] FIG. 8. Schematics and 3D printing results of three representative stent structures.

show abstract

Section: Resultsmentioning

confidence: 99%

Experimental study of polymeric stent fabrication using homemade 3D printing system

Zhao

Zhou

Sun³

et al. 2019

Polymer Engineering & Sci

View full text Add to dashboard Cite

show abstract

“…[ 2 ] Percutaneous coronary intervention (PCI) [ 3 ] is the standard interventional treatment in which a metal stent is deployed via a balloon catheter to reopen the affected vessel segment, with over 3 million coronary devices deployed in the USA, Europe, and China per annum. [ 4 ] Despite advances in technology a hyperplastic wound response termed in‐stent restenosis (ISR) often re‐blocks the stent in 5–10% of cases. Within 18 months these vessels can become reoccluded as cells slowly grow across the device struts.…”

Section: Introductionmentioning

confidence: 99%

“…[ 8 ] DES have significantly lowered patient readmittance rates for target lesion revascularization (2.91% versus 12.32%). [ 9 ] Yet with so many PCI procedures being performed globally, [ 4 ] an estimated 100 000 patients still suffering life changing complications. Improvements in stent design such as reduction in stent strut thickness and drug elution coatings have also driven some improvements.…”

Section: Introductionmentioning

confidence: 99%

Predicting Cardiovascular Stent Complications Using Self‐Reporting Biosensors for Noninvasive Detection of Disease

et al. 2022

View full text Add to dashboard Cite

Self‐reporting implantable medical devices are the future of cardiovascular healthcare. Cardiovascular complications such as blocked arteries that lead to the majority of heart attacks and strokes are frequently treated with inert metal stents that reopen affected vessels. Stents frequently re‐block after deployment due to a wound response called in‐stent restenosis (ISR). Herein, an implantable miniaturized sensor and telemetry system are developed that can detect this process, discern the different cell types associated with ISR, distinguish sub plaque components as demonstrated with ex vivo samples, and differentiate blood from blood clot, all on a silicon substrate making it suitable for integration onto a vascular stent. This work shows that microfabricated sensors can provide clinically relevant information in settings closer to physiological conditions than previous work with cultured cells.

show abstract

Heating/Solvent Responsive Shape‐Memory Polymers for Implant Biomedical Devices in Minimally Invasive Surgery: Current Status and Challenge

Xiao

Huang

2020

Macromolecular Bioscience

View full text Add to dashboard Cite

This review is about the fundamentals and practical issues in applying both heating and solvent responsive shape memory polymers (SMPs) for implant biomedical devices via minimally invasive surgery. After revealing the general requirements in the design of biomedical devices based on SMPs and the fundamentals for the shape‐memory effect in SMPs, the underlying mechanisms, characterization methods, and several representative biomedical applications, including vascular stents, tissue scaffolds, occlusion devices, drug delivery systems, and the current R&D status of them, are discussed. The new opportunities arising from emerging technologies, such as 3D printing, and new materials, such as vitrimer, are also highlighted. Finally, the major challenge that limits the practical clinical applications of SMPs at present is addressed.

show abstract

Of Stents and Scaffolds

Abstract: Figure.The influence of patient-related factors on outcomes after percutaneous coronary intervention when comparing different devices can be avoided with an intraindividual comparison. The effect of lesion-related factors can be mitigated by randomization.by guest on

Cited by 3 publications

References 17 publications

Experimental study of polymeric stent fabrication using homemade 3D printing system

Experimental study of polymeric stent fabrication using homemade 3D printing system

Predicting Cardiovascular Stent Complications Using Self‐Reporting Biosensors for Noninvasive Detection of Disease

Heating/Solvent Responsive Shape‐Memory Polymers for Implant Biomedical Devices in Minimally Invasive Surgery: Current Status and Challenge

Contact Info

Product

Resources

About