Oleoresin Capsicum toxicology evaluation and hazard review

Archuleta, Melecita M.

doi:10.2172/120857

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Capsaicinoids Content2

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Cited by 4 publications

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“…23 In addition, its remarkable taste and bioactivity, 22,56,89 as previously cited in this article and discussed by Wahyuni et al, CAPS presents a high toxicity degree to humans. 56 In mammalian organism, CAPS act as an inammatory and carcinogenic agent 18,41,90 causing irritation in mucous membranes in the digestive and respiratory systems and cellular rupture, when orally ingested. 28,35,36 It is estimated that the 50% of the CAPS lethal dose by oral ingestion in humans is 5.0 g kg À1 , 40,41 with a safe daily intake dose of 2.64 mg of CAPS.…”

Section: Capsaicinoids Contentmentioning

confidence: 99%

“…For medicinal proposes, cultivars with moderate to low CAPS content are preferable due to the alkaloid toxicity, that can make it difficult to formulate medicines that are safe to be used by humans. 18,90,91 In the food industry and for military usage, it is desirable that a product contains a large concentration of CAPS. Thus, cultivars with moderate to high CAPS content are usually applied.…”

Section: Capsaicinoids Contentmentioning

confidence: 99%

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