“…The emission wavelength of QCLs covers the mid-and long-infrared region from l¼2.6 to l¼25 mm and part of the terahertz region of the spectrum [2,3], which opens up many immediate or potential applications in chemical and biological sensing, spectroscopy, astronomy and medical imaging. While tremendous progress has been made in improving the device performance via QCL structure design since its first demonstration in 1994 [4][5][6][7][8][9][10][11][12][13], there are few studies on the epitaxial growth itself [14][15][16][17], which, indeed, represents one of the most challenging tasks for semiconductor material growers. The QCL structure, with total thickness easily exceeding 10 mm and number of layers close to thousand, requires a precise control over the composition, thickness, background doping, and interface abruptness of each layer.…”