In this paper, we have investigated the physical layer security over cascaded Fisher-Snedecor F fading channels in the presence of randomly distributed eavesdroppers. To characterize the eavesdroppers' intercept capability, both the conceptual k-th nearest and best eavesdroppers are introduced. The probability density function (PDF) of the k-th nearest and best eavesdropper is characterized. The probability of interception, Pint, is correspondingly regarded as the secrecy metric, and is further derived with closed-form expressions in terms of Fox's H-function. For the purposes of providing more insights, the asymptotic behavior of the intercept probability is also provided. To explore the effects of the eavesdroppers' density and the channel fading conditions on the secrecy performance, we have performed the Monte-Carlo simulation and compared our analytical results with the simulated ones. One can find that our analytical results are successfully verified by the simulation results.