On the Electrophoretic Behavior of Thermal Polymers of Amino Acids

Dose, Klaus; Rauchfuss, Horst

doi:10.1007/978-1-4684-2019-7_17

Cited by 23 publications

(1 citation statement)

References 7 publications

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“…The self-ordering of amino acids that is so critical has been verified by Dose and Rauchfuss (1972), verified and extended by Tyagi and Ponnamperuma (1990), and shown to have evolutionary meaning by Ivanov and Fortsch (1986). The sterochemistry is that.…”

Section: Chronology In the Laboratorymentioning

confidence: 85%

Experimental Retracement of Terrestrial Origin of an Excitable Cell: Was it Predictable?

Fox

Bahn²,

Pappelis³

et al. 1996

Chemical Evolution: Physics of the Origin and Evolution of Life

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A largely historical treatment of how the evolutionary sequence to the first synthesis of life under terrestrial conditioJls, as retraced in the laboratory, is presented. The insights of such pioneers as Pasteur on self-organization of matter to "beings" are related. The recent acknowledgment of fruitless attempts by experts in DNA-first. RNA-first. and in irrelevance of the concept of random beginnings are cited. Updating of origins from amino acid-instructed genetically primary thermal protein is detailed. The essence of the finding of internal nonrandomness is emphasized, as well as the critical nature of studying the initial steps of molecular evolution in a synthetic direction. The total flowsheet for amino acid precursors -+ protocell = protoneuron is updated. The results of eXlleriments are tested against the characteristics of life as it is usually defined: metabolism, growth, reproduction, and response to stimuli such as light.Experimentally derived reasons for inferring that the origin of excitability and conscious mind were co-existent with the origin of the membranous cell arc given. The principal source of excitability is found from flavins formed by heating of amino acid mixtures containing excitatory aspanic acid and glutamic acid which copolymerize thermally. HISTORYLast year (Fox et aI, 1995) we retraced the pictorial evidence and cited the tabular evidence for the synthesis in the laboratory from evolutionary events of a living cell. In this presentation, I plan to explain how the research itself evolved.Historically, two of the most significant ideas leading to the synthesis of life can now be traced from the theoretical emphases of Louis Pasteur as based on the shapes of molecules (Degani, 1995) and Pasteur's thoughts on the self-organization of matter of a kind (Fox and Dose, 1972) he could not have been expected to identify in the I860s. However, Darwin did specify a "protein compound" in 1871 in a letter to a friend (Fox and Dose, 1972).

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Section: Chronology In the Laboratorymentioning

confidence: 85%