On the Integration of Agents and Digital Twins in Healthcare

Croatti, Angelo; Gabellini, Matteo; Montagna, Sara; Ricci, Alessandro

doi:10.1007/s10916-020-01623-5

Cited by 218 publications

(117 citation statements)

References 20 publications

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“…Instead of creating a wholistic model, several studies also focused on assisting our understanding or management of a target condition or class of conditions with digital twins. One application was described in a case study of trauma management [ 21 ], where the authors proposed a ‘mirror world’ that captured not only the trauma patient but also the patient’s surrounding environment. The goal of this study was to capture important and relevant contextual information around the patient (e.g., the hospital environment, physicians, or trauma team of contact) via ‘cognitive, social, and temporal augmentations’.…”

Section: Digital Twins In Personalised Medicinementioning

confidence: 99%

Digital Twins: From Personalised Medicine to Precision Public Health

Boulos

Zhang

2021

JPM

249

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A digital twin is a virtual model of a physical entity, with dynamic, bi-directional links between the physical entity and its corresponding twin in the digital domain. Digital twins are increasingly used today in different industry sectors. Applied to medicine and public health, digital twin technology can drive a much-needed radical transformation of traditional electronic health/medical records (focusing on individuals) and their aggregates (covering populations) to make them ready for a new era of precision (and accuracy) medicine and public health. Digital twins enable learning and discovering new knowledge, new hypothesis generation and testing, and in silico experiments and comparisons. They are poised to play a key role in formulating highly personalised treatments and interventions in the future. This paper provides an overview of the technology’s history and main concepts. A number of application examples of digital twins for personalised medicine, public health, and smart healthy cities are presented, followed by a brief discussion of the key technical and other challenges involved in such applications, including ethical issues that arise when digital twins are applied to model humans.

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Section: Digital Twins In Personalised Medicinementioning

confidence: 99%

Digital Twins: From Personalised Medicine to Precision Public Health

Boulos

Zhang

2021

JPM

249

View full text Add to dashboard Cite

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“…For example, [13] uses body-on-a-chip (BOC) to understand the effects of certain drugs on patients. [21]- [23] applies VR technologies to synchronise surgical procedures so as to realise digital surgery.…”

Section: The Application Of Digital Twins In Industriesmentioning

confidence: 99%

Digital Twin in Aerospace Industry: A Gentle Introduction

et al. 2022

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Digital twin (DT), primarily a virtual replica of any conceivable physical entity, is a highly transformative technology with profound implications. Whether it be a product development, design optimisation, performance improvement, or predictive maintenance, digital twins are changing the ways work is undertaken in various industries with multifarious business applications. Aerospace industry, including its manufacturing base, is one such keen adopter of digital twins with an unprecedented interest in their bespoke design, development, and implementation across wider operations and critical functions. This, however, comes with some misconceptions about the digital twin technology and lack of understanding with respect to its optimal implementation. For instance, equating digital twin to an intelligent model while ignoring the essential components of data acquisition and visualisation, misleads the creators into building digital shadow or digital models, instead of the actual digital twin. This paper unfolds such intricacies of digital twin technology for the aerospace community in particular and others in general so as to remove the fallacies that affect their effective realisation for safety-critical systems. It comprises a comprehensive survey of digital twins and their constituent elements. Elaborating their characteristic stateof-the-art composition along with corresponding limitations, three dimensions of the future digital twins for aerospace sector, termed as aero-Digital Twins (aero-DTs), are proposed as an outcome of this survey. These include the interactive, standardisation, and cognitive dimensions of digital twins, which if leveraged diligently could help the aero-DT research and development community quadruple the efficiency of existing and future aerospace systems as well as their associated processes.

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“…A WoDT is meant to serve as a blueprint to shape that idea of ecosystem from a computational point of view. The term physical asset (PA) mentioned in the principle is intentionally used as a broad term, to include any entity that has some kind of manifestation and relevance in the physical world of the organisation, with a well deined temporal lifespan 9 . It can include physical objects/resources, places, persons, but also activities and processes carried on by people in places.…”

Section: Overviewmentioning

confidence: 99%

Web of Digital Twins

Ricci

Croatti

Mariani

et al. 2022

ACM Trans. Internet Technol.

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In recent years, digital twins have been pervading different application domains – from manufacturing to healthcare – as an approach for virtualising different kinds of physical entities (things, products, machines). The dominant view developed in the literature so far is about the virtualisation of individual physical assets, in a closed-system perspective. In this paper, we introduce and explore a broader perspective that we call Web of Digital Twins (WoDT), in which the digital twin paradigm is exploited for the pervasive softwarisation of possibly large-scale interrelated physical realities. A WoDT can be conceived as an open, distributed and dynamic ecosystem of connected digital twins, functioning as an interoperable service-oriented layer for applications running on top, especially smart applications and multiagent systems. The paper introduces an abstract model and architecture aimed to capture key aspects of the idea not bound to any specific application domains or implementing technologies, and discusses their adoption in engineering real-world systems. To this purpose, two concrete case studies are considered, in the context of healthcare and smart mobility. Finally, the paper includes a discussion of a selected set of research directions.

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On the Integration of Agents and Digital Twins in Healthcare

Cited by 218 publications

References 20 publications

Digital Twins: From Personalised Medicine to Precision Public Health

Digital Twins: From Personalised Medicine to Precision Public Health

Digital Twin in Aerospace Industry: A Gentle Introduction

Web of Digital Twins

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