2018
DOI: 10.1007/s10967-018-5772-x
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One-step conjugation of glycylglycine with [18F]FDG and a pilot PET imaging study

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Cited by 9 publications
(3 citation statements)
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“…Senisik et al also describe a single-step, high-efficiency conjugation of glycylglycine (GlyGly), which is a small peptide, with [ 18 F] FDG, without the need for purification. Researchers without cyclotron facilities can easily perform efficient radiolabeling and use [ 18 F] FDG-GlyGly to improve biodistribution studies [40].…”
Section: Glucosementioning
confidence: 99%
“…Senisik et al also describe a single-step, high-efficiency conjugation of glycylglycine (GlyGly), which is a small peptide, with [ 18 F] FDG, without the need for purification. Researchers without cyclotron facilities can easily perform efficient radiolabeling and use [ 18 F] FDG-GlyGly to improve biodistribution studies [40].…”
Section: Glucosementioning
confidence: 99%
“…The very simple procedure for using clinically readily available FDG for ligation with peptides was demonstrated using the small peptide glycylglycine as an example [73]. Starting from the commercially available [ 18 F]FDG solution and after cleavage of the BOC protecting group from the aminooxy-derivatized peptide, [ 18 F]FDG-GlyGly (60) could be obtained in a RCY of 98% at 100 • C after 30 min.…”
Section: [ 18 F]fdg For Chemoselective 18 F-fluoroglycosylation By Oxime Linkagementioning
confidence: 99%
“…The very simple procedure for using clinically readily available FDG for ligation with peptides was demonstrated using the small peptide glycylglycine as an example [74]. Starting from the commercially available [ 18 F]FDG solution and after cleavage of the BOC protecting group from the aminooxy-derivatized peptide, [ 18 F]FDG-GlyGly (60) could be obtained in a RCY of 98% at 100°C after 30 min.…”
Section: [ 18 F]fdg For Chemoselective 18 F-fluoroglycosylation By Oxime Linkagementioning
confidence: 99%