OP03.17: The cisterna magna septa—a potential new marker for maldevelopment of the roof of the rhombencephalon

Robinson, Ashley; Goldstein, Ruth B.

doi:10.1002/uog.3124

Cited by 22 publications

(53 citation statements)

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“…They suggest that delay or failure of the pouch to fenestrate is associated with cerebellar rotation without vermis malformation. However, a sagittal histologic section of vermis, which was available for only one of their cases (Robinson and Goldstein, 2007, Fig. 12), showed the same nodulus abnormalities as in our series and raises concern that subtle vermis pathology may be present.…”

Section: Why Is Concordance Poor Betweenmentioning

confidence: 41%

“…Others have hypothesized that enlargement of the fourth ventricle and vermian rotation alone may produce abnormal axial ultrasound images, which mimic features associated with vermis hypoplasia (Barkovich et al, 1989;Zalel et al, 2006;Robinson and Goldstein, 2007). Robinson and Goldstein (2007) interpreted some forms of isolated fourth ventricular dilation as persistence of Blake's pouch, a dorsal evagination of the rhombencephalon that normally fenestrates and collapses by the fourth month of gestation. They suggest that delay or failure of the pouch to fenestrate is associated with cerebellar rotation without vermis malformation.…”

Section: Why Is Concordance Poor Betweenmentioning

confidence: 97%

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Normal and abnormal anatomy of the cerebellar vermis in midgestational human fetuses

Kapur

Mahony

Finch

et al. 2009

Birth Defects Research

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Prenatal ultrasound images that suggest moderate-to-severe hypoplasia of the cerebellar vermis may reflect relatively subtle malformations, which are recognized histologically by direct comparison with stage-matched control data. The data in this series and others suggest a somewhat consistent pattern of lobular malformation, which affects the caudal cerebellum, particularly the nodulus, most severely. Rotation of the cerebellum, secondary to an enlarged fourth ventricle, may account for discordance between ultrasound and autopsy findings.

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Section: Why Is Concordance Poor Betweenmentioning

confidence: 41%

Section: Why Is Concordance Poor Betweenmentioning

confidence: 97%

Normal and abnormal anatomy of the cerebellar vermis in midgestational human fetuses

Kapur

Mahony

Finch

et al. 2009

Birth Defects Research

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“…The DWC includes classic Dandy-Walker malformation (DWM), Dandy-Walker variant, and possibly also mega cisterna magna and persistent Blake pouch cyst, 31,37 although, for the purposes of this paper, the latter two are considered separately in the final section. Fetuses with disorders in this continuum can have normal outcomes or can be syndromic with poor outcomes.…”

Section: Dandy-walker Continuummentioning

confidence: 99%

“…41 Classic DWM was initially described in infants with hydrocephalus and was thought to be the sequelae of atresia of foramina of Luschka and Magendie. 42Y44 However, current theories suggest that it is a more global developmental defect affecting the area membranacea of the roof of the rhombencephalon, 18,31 leading to variable degrees of vermian hypoplasia, variable fenestration of the fourth ventricular outlet foramina, and variable associated anomalies.…”

Section: Dandy-walker Continuummentioning

confidence: 99%

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The Fetal Cerebellar Vermis

Robinson¹,

Blasér²,

Toi³

et al. 2007

Ultrasound Quarterly

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Fetal magnetic resonance provides a new tool in the imaging of the posterior fossa and is proving useful in cases that are difficult to assess sonographically by allowing further assessment of the fourth ventricle, cisterna magna, and vermian growth and development. We describe various criteria with which to evaluate vermian growth, including vermian biometry and the relationship between the superior and inferior lobes. We demonstrate 2 markers of normal vermian development: the primary fissure and fastigial point. We illustrate the tegmento-vermian angle, "closure" of the fourth ventricle, and communication of the fourth ventricle with the basal cisterns during development and in several disorders. We correlate those features with the expected embryological course of development and illustrate identification of these features and associated abnormalities of the posterior fossa, brain stem, and central nervous system in mid-trimester scans of fetuses with abnormal development. Correlation with contemporaneous ultrasound examinations is demonstrated.

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Dilated intracranial translucency and blake's pouch cyst: First‐trimester ultrasound markers of occipital cephalocele diagnosed using novel three‐dimensional reslicing technique

Tonni

Grisolia

2013

J of Clinical Ultrasound

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Abnormal intracranial translucency (IT) (fourth ventricle) and a Blake's pouch cyst with normal brain stem cavity may be valuable first-trimester call signs of defects in the skull base. Here, we report a case of presumptive two-dimensional sonographic diagnosis of occipital cephalocele that was posed at the time of 11-13 weeks aneuploidy scan. The two-dimensional sonographic finding elicited a detailed fetal neuroscan that was performed using either multiplanar mode or a novel three-dimensional reslicing and lightening technique. The use of three-dimensional sonographic software and offline "navigation" within the volume of interest enabled operators to capture a diagnostic snapshot of the condition, enhancing quality imaging and early detection of the encephalic lesion.

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OP03.17: The cisterna magna septa—a potential new marker for maldevelopment of the roof of the rhombencephalon

Cited by 22 publications

References 0 publications

Normal and abnormal anatomy of the cerebellar vermis in midgestational human fetuses

Normal and abnormal anatomy of the cerebellar vermis in midgestational human fetuses

The Fetal Cerebellar Vermis

Dilated intracranial translucency and blake's pouch cyst: First‐trimester ultrasound markers of occipital cephalocele diagnosed using novel three‐dimensional reslicing technique

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