Optic Disk Vasculitis

Optic disc vasculitis

“…Our critical evaluation of the cases reported under the eponyms of "retinal vasculitis" [26], "papillophlebitis" [25], "mild retinal and papillary vasculitis" [8], and "benign retinal vasculitis" [10] reveals that in fact all of them belonged to the category of non-ischemic CRVO in young persons. Similarly, cases described by some authors as "optic disc vasculitis" [2,4,6] and "optic disc vasculitis type II" [12] were in fact CRVO in young persons and not true ODV as described in the present study. Histopathological evidence indicates that inflammatory infiltration of the intraneural part of the central retinal vein may cause CRVO in young adults either by its invasion of the lumen or by thrombosis [2,3,7,8,24].…”

“…Similarly, cases described by some authors as "optic disc vasculitis" [2,4,6] and "optic disc vasculitis type II" [12] were in fact CRVO in young persons and not true ODV as described in the present study. Histopathological evidence indicates that inflammatory infiltration of the intraneural part of the central retinal vein may cause CRVO in young adults either by its invasion of the lumen or by thrombosis [2,3,7,8,24]. Thus, in all the cases described under various names above, the cause of fundus lesions may be a variable degree of phlebitis in the intraneural part of the central retinal vein.…”

“…Thus, from Hayreh's original description [12], only ODV type I could be considered true ODV. To date, only three additional papers have been published describing cases of "optic disc vasculitis"; however, a critical review of those papers revealed that in two of them the patients had non-ischemic CRVO [4,6] and in one, ischemic CRVO [2].…”

The main aspects of retinal vein occlusion etiopathogenisis in young adults. Part I. Neuroretinovasculitis (prothrombotic potential, clinical manifestations)

“…В большинстве работ этиологический фактор воспалительного процесса обнаружен не был, при этом ряд авторов связывал его с болезнью Ильза [42], системной красной волчанкой и системными васкулитами [17]. О том, что ОВС предшествовало воспаление сосудистой стенки ретинальных вен, свидетельствовала не только характерная клиническая картина, но и данные гистологических исследований, выявивших мононуклеарную инфильтрацию ЦВС и выраженный флебит сосудов зрительного нерва [12].…”

Central Retinal Vein Occlusion: Review of Management

“…Histopathologic studies of the thrombotic central retinal vein have disclosed chronic inflammatory changes and perivenular infiltration by round cells, which most likely is the result and not the cause of CRVO (1,59). Recanalization of the vein usually occurs over time (1,54,60).…”