Optimization of extracellular glucan production from Pleurotus eryngii and its impact on angiogenesis

Shenbhagaraman, R.; Jagadish, L.; Premalatha, Kishorekumar; Kaviyarasan, V.

doi:10.1016/j.ijbiomac.2012.02.008

Cited by 15 publications

(7 citation statements)

References 40 publications

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“…The Morris water maze test showed that spatial memory impairment in OVX rats was improved by PEE. These results suggested that PEE has estrogen-like activity, which can improve depression-like behaviour and memory impairment in OVX rats [40][41][42].…”

Section: Estrogen-like Activitymentioning

confidence: 75%

A Potent Pharmacological Mushroom: Pleurotus eryngii

Fu¹,

Liu²

2016

Fungal Genom Biol

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Pleurotus eryngii, commonly known as the king oyster mushroom, has been used extensively in North Africa, Europe and Asia. A great deal of work has been carried out on therapeutic potential of Pleurotus eryngii. The edible Fungi perform multiple bioactivities: anticancer, antiviral, antioxidant, antimicrobial, anti-leukaemia, hypolipidemic, immuno-modulating and estrogen-like activity. These bioactive properties depend on its bioactive compounds such as polysaccharides, eryngiolide A, ubiquinone-9, pentacyclic triterpenoid and so on. The present review focuses on the potential pharmacological activities and provides reference for the study of Pleurotus eryngii in the future.

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Section: Estrogen-like Activitymentioning

confidence: 75%

A Potent Pharmacological Mushroom: Pleurotus eryngii

Fu¹,

Liu²

2016

Fungal Genom Biol

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“…Another possible mechanism of the impact of β -glucans on immune cells is the interaction of these polysaccharides with the CR3 receptors [7, 8]. Besides their action on immune cells, β -glucans also inhibit angiogenesis by cutting off the supply of nutrients to tumor cells and, in consequence, inhibiting their development [9]. …”

Section: Introductionmentioning

confidence: 99%

Exopolysaccharide fromGanoderma applanatumas a Promising Bioactive Compound with Cytostatic and Antibacterial Properties

Osińska-Jaroszuk

Jaszek

Mizerska-Dudka

et al. 2014

BioMed Research International

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A new exopolysaccharide preparation isolated from stationary cultures of the white rot fungus Ganoderma applanatum (GpEPS) was tested in terms of its bioactive properties including its cytotoxic and immunostimulatory effect. The results indicate that the tested GpEPS (at concentrations above 22.85 µg/mL and 228.5 µg/mL) may exhibit selective activity against tumor cells (cell lines SiHa) and stimulate production of TNF-α THP-1-derived macrophages at the level of 752.17 pg/mL. The GpEPS showed antibacterial properties against Staphyloccoccus aureus and a toxic effect against Vibrio fischeri cells (82.8% cell damage). High cholesterol-binding capacity and triglycerides-binding capacity (57.9% and 41.6% after 24 h of incubation with the tested substances, resp.) were also detected for the investigated samples of GpEPS.

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“…Antioxidant character of this mushroom seems to be doubtless (ALAM et al, 2011). Intracellular β-glucan molecules can affect the immune system (CARBONERO et al, 2006), extracellular glucan molecules (produced by mycelium culture) have anti-angiogenetic properties against tumours (SHENBHGARAMAN et al, 2012). P. eryngii could be recommended as a cholesterol decreasing component (ALAM et al, 2011) and can improve insulin-sensitivity.…”

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confidence: 99%

Chemical analysis of king oyster mushroom (Pleurotus eryngii) fruitbodies

2016

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King oyster mushroom (Pleurotus eryngii) is a worldwide cultivated mushroom of appreciated nutritional and medicinal quality. Aims of these investigations were to give new comparative data for the better evaluation of P. eryngii. Results of our investigations can be summarized as follows:P. eryngii has higher (crude protein, crude fat) or at least the same concentrations (chitin and total carbohydrate) of organic nutritive components than the common cultivated Pleurotus hybrid ('HK-35'). Regarding the classical protein fractions: albumins are the highest content in both mushrooms, but the quantity and the proportion in P. eryngii is better than in 'HK-35' hybrid. Occurrence and proportion of protein fractions is more valuable in P. eryngii, while the NPN contents of both mushrooms are the same.The investigated soluble oligo-and polysaccharides were present in high amounts in both mushrooms, but the free radical scavenging activity seems to be markedly higher in king oyster mushroom, making it more valuable. Mineral compositions of both species are similarly benefi cial, but P. eryngii has basically higher P and lower K levels. More intensive cultivation and use of P. eryngii is clearly recommended.

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Optimization of extracellular glucan production from Pleurotus eryngii and its impact on angiogenesis

Cited by 15 publications

References 40 publications

A Potent Pharmacological Mushroom: Pleurotus eryngii

A Potent Pharmacological Mushroom: Pleurotus eryngii

Exopolysaccharide fromGanoderma applanatumas a Promising Bioactive Compound with Cytostatic and Antibacterial Properties

Chemical analysis of king oyster mushroom (Pleurotus eryngii) fruitbodies

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