and multiplication avalanche photodiodes (SAM-APDs) composed of photoabsorbers and large bandgap multiplication regions are advantageous for achieving highefficient and low-noise photodetection with high-energy resolution. [11][12][13] Such a detector architecture can be also applied to energy-sensitive gamma-ray and X-ray detection. A GaAs/AlGaAs SAM-APD comprised of a 4.5 µm absorption region and a staircase-like multiplication region has been developed for X-ray photodetection. [14] Meanwhile, a similar GaAs/ Al 0.8 Ga 0.2 As SAM-APD structure has been also demonstrated to detect soft X-rays at 5.9 keV with a full-width half-maximum (FWHM) of 1.08 keV. [15] However, its spectroscopic characterizations show an undesired secondary peak located at energy lower than the 5.9 keV peak. This is because of 1) different degrees of impact ionization experienced by the electrons and holes; [16][17][18] 2) insufficient layer thickness ratio; [19] and 3) inadequate difference of pair creation energy (PCE) between GaAs and AlGaAs. [20,21] Indeed, the absorption efficiency can be improved by simply increasing the thickness of the absorption layer. Unfortunately, the commonly used (Al)GaAs semiconductors are not able to concurrently offer high-Z (i.e., high atomic number) absorption and large PCE difference within SAM structures for highenergy X-ray or gamma-ray detection.Alternatively, the antimony-based (Sb-based) SAM-APD structure with high-Z GaSb and large bandgap AlAsSb is promising. GaSb absorbers can provide a much higher probability than GaAs to stop X-ray and gamma-ray photons at a given energy due to a relatively higher Z. [22] In addition, the GaSb/AlAsSb material system provides a larger dissimilarity in both PCE and absorption efficiency. [23,24] This allows for a significant suppression of spurious photopeaks, which are generated outside the intended absorption regions. The combination of these unique capabilities shows promise for achieving X-ray and gamma-ray detectors with high spectroscopic performance. To prove the concept, we develop GaSb/AlAsSb SAM-APDs composed of 2 µm GaSb absorbers and AlAsSb digital alloy multiplication regions to detect X-ray and gamma-ray photopeaks under irradiation from 241 Am sources. Due to the reduced high-peak electric Demonstrated are antimony-based (Sb-based) separate absorption and multiplication avalanche photodiodes (SAM-APDs) for X-ray and gamma-ray detection, which are composed of GaSb absorbers and large bandgap AlAsSb multiplication regions in order to enhance the probability of stopping highenergy photons while drastically suppressing the minority carrier diffusion. Well-defined X-ray and gamma-ray photopeaks are observed under exposure to 241 Am radioactive sources, demonstrating the desirable energy-sensitive detector performance. Spectroscopic characterizations show a significant improvement of measured energy resolution due to reduced high-peak electric field in the absorbers and suppressed nonradiative recombination on surfaces. Additionally, the GaSb/AlAsSb SAM...