Optimization of skin dose using<i>in‐vivo</i><scp>MOSFET</scp>dose measurements in bolus/non‐bolus fraction ratio: A<scp>VMAT</scp>and a 3<scp>DCRT</scp>study

Dias, A.G.; Pinto, Daniel; Borges, Maria F.; Pereira, Maria H.; Domingues, Inês; Cunha, Lídia; Lencart, Joana

doi:10.1002/acm2.12525

Cited by 18 publications

(17 citation statements)

References 33 publications

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“…There is evidence of skin toxicity in breast radiotherapy, especially in friction regions such as the axilla and skin folds. 1 There are multiple criteria to evaluate the degree of acute and late toxicity in the skin associated with the use of radiotherapy, such as the Radiation Therapy Oncology Group (RTOG) and the Common Terminology Criteria for Adverse Events (CTCAE). Both classifications consider acute reactions according to the severity of the injury caused to the skin.…”

Section: Introductionmentioning

confidence: 99%

Experimental determination of breast skin dose using volumetric modulated arc therapy and field-in-field treatment techniques

Cardona-Maya¹,

Rojas-López

Germanier

et al. 2022

J Radiother Pract

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Introduction: The use of volumetric modulated arc therapy (VMAT) on the breast has several dosimetric advantages but its impact on skin dose should be evaluated and compared to well-established treatment techniques using tangential fields. The aim of this work is to contrast the skin dose for VMAT and field-in-field (FIF) and to estimate the magnitude of the skin dose involved. Method: The skin dose was measured, without build-up, using thermoluminescent dosimeter (TLD) and optically stimulated luminescence dosimeter (OSLD) in breast radiotherapy by an in-house anthropomorphic phantom. Two different treatment techniques were used: FIF and VMAT, based on the planning strategy proposed by Nicolini et al. The dose levels were 4300 cGy, 4600 cGy and 5600 cGy in 20 fractions. In vivo dosimetry with TLD for VMAT was performed for different breast sizes in the same locations as phantom measurements. Results: The ipsilateral phantom breast skin dose using both treatment techniques was equivalent. TLD measured doses by the VMAT technique were up to 5% higher than OSLD, although they agree if we consider the geometry uncertainty of the TLD. In accordance with in vivo dosimetry, the mean dose of the ipsilateral breast skin was 62 ± 6% (51%, 75%) relative to the prescribed dose, regardless of the breast size for the volumes considered with this small population (n = 9) as shown by Mann–Whitney U-test (Z = 1·9, 95% confidence). The uncertainty expected in this region due to geometry (volume) changes is up to 9% higher for volumes from 225·9 cc to 968·8 cc. According to the treatment techniques and in vivo dosimetry, the contralateral breast skin dose was 1·0% in FIF and 2·5% in VMAT concerning the prescribed dose. Conclusion: There is no difference in skin dosimetry between VMAT and FIF techniques on the ipsilateral breast. It provides useful support for the use of VMAT as a planning technique for breast irradiation. The work describes the importance of quantifying potential differences in skin dosimetry.

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Section: Introductionmentioning

confidence: 99%

Experimental determination of breast skin dose using volumetric modulated arc therapy and field-in-field treatment techniques

Cardona-Maya¹,

Rojas-López

Germanier

et al. 2022

J Radiother Pract

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“…In addition, the skin surface is naturally curved, and positional accuracy of the dosimeters can affect the verification of the therapeutic doses in clinical practice. For instance, the MOSFET dosimeter exhibits sensitivity variations from 5% to 22.8% depending on its angular location during radiation therapy [10,11]. To overcome this issue, studies have focused on developing flexible dosimeters with functional materials [12][13][14].…”

Section: Introductionmentioning

confidence: 99%

An investigation on quantitative detector characteristics of novel flexible skin dosimeter using Monte Carlo simulation method

Kaya

2022

Journal of New Results in Science

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Novel lead oxide-based flexible dosimeters with superior performance were experimentally tested for electron therapy. However, absorbed/transmitted primary particle fraction and secondary radiation distribution from the dosimeter surface have not been reported. These features should be specified to improve the dosimeter’s reliability for medical applications. Hence, the absorbed primary particle fraction, transmitted particle and secondary radiations distributions of lead oxide-based flexible skin dosimeter under the incident 6 MeV electron radiation have been investigated by pyPenelope Monte Carlo Simulation. The results have demonstrated that the generated secondary irradiation probabilities are not significantly high to enhance the therapeutic dose abnormally. In addition, the angular distribution of the scattered secondary irradiations is low. No abnormal changes were observed in the fraction and energy distribution of the transmitted primary electrons. Hence, it can be concluded that the designed structure has promising potential to be used as dosimeters in electron beam therapy.

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“…Additionally, as the attachment part on a patient’s body, which is naturally curved, is checked visually, the positional accuracy can be unreliable [ 6 ]. For example, the average error rate of a digital MOSFET dosimeter was reported to be 22.8% [ 7 ]. Therefore, in clinical practice, there is an urgent demand for a patch-type digital surface dosimeter that can be attached to a patient’s skin to measure the body surface in real time.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy

et al. 2021

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Generally, electron therapy is applied to tumors on or close to the skin surface. However, this causes a variety of skin-related side effects. To alleviate the risk of these side effects, clinical treatment uses skin dosimeters to verify the therapeutic dose. However, dosimeters suffer from poor accuracy, because their attachment sites are approximated with the help of naked eyes. Therefore, a dosimeter based on a flexible material that can adjust to the contours of the human body is required. In this study, the reproducibility, linearity, dose-rate dependence, and percentage depth ionization (PDI) of PbO and HgO film-based dosimeters are evaluated to explore their potential as large-scale flexible dosimeters. The results demonstrate that both dosimeters deliver impressive reproducibility (within 1.5%) and linearity (≥ 0.9990). The relative standard deviations of the dose-rate dependence of the PbO and HgO dosimeters were 0.94% and 1.16% at 6 MeV, respectively, and 1.08% and 1.25% at 9 MeV, respectively, with the PbO dosimeter outperforming the 1.1% of existing diodes. The PDI analysis of the PbO and HgO dosimeters returned values of 0.014 cm (–0.074 cm) and 0.051 cm (–0.016 cm), respectively at 6 MeV (9 MeV) compared to the thimble chamber and R50. Therefore, the maximum error of each dosimeter is within the allowable range of 0.1 cm. In short, the analysis reveals that the PbO dosimeter delivers a superior performance relative to its HgO counterpart and has strong potential for use as a surface dosimeter. Thus, flexible monoxide materials have the necessary qualities to be used for dosimeters that meet the requisite quality assurance standards and can satisfy a variety of radiation-related applications as flexible functional materials.

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Optimization of skin dose usingin‐vivoMOSFETdose measurements in bolus/non‐bolus fraction ratio: AVMATand a 3DCRTstudy

Cited by 18 publications

References 33 publications

Experimental determination of breast skin dose using volumetric modulated arc therapy and field-in-field treatment techniques

Experimental determination of breast skin dose using volumetric modulated arc therapy and field-in-field treatment techniques

An investigation on quantitative detector characteristics of novel flexible skin dosimeter using Monte Carlo simulation method

Evaluation of monoxide film-based dosimeters for surface dose detection in electron therapy

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