Optimum dose and time of pregnant mare serum gonadotropin injections in Kacang goats to increase endogenous secretion of estrogen and progesterone without superovulation response

Andriyanto,; Amrozi, .; Rahminiwati, Min; Boediono, Arief; Manalu, Wasmen

doi:10.1016/j.smallrumres.2017.02.005

Cited by 8 publications

(9 citation statements)

References 25 publications

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“…The improved uterine environment and the optimum condition during prenatal growth will optimize the genetic expressions of the birth lambs that will improve the growth and survival of the offspring during postnatal life. Since the superovulation by using commercial gonadotropin hormone is expensive and has a side effect of increased litter size, our team also designed the optimum dose for stimulating the endogenous secretion of Pg and estradiol without increasing litter size in Kacang goats [ 46 ].…”

Section: Discussionmentioning

confidence: 99%

Potential use of Indonesian basil (Ocimum basilicum) maceration to increase estradiol and progesterone synthesis and secretion to improve prenatal growth of offspring using female albino rats as an animal model

et al. 2022

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Background and Aim: Basil is well known as a medicinal plant that contains high essential oils and antioxidant compounds that have the potential to improve ovarian development. Thus, basil may have the potential to improve the growth and development of the uterus and placenta for optimal prenatal growth of offspring. This study aimed to evaluate the effect of Indonesian basil maceration on gonad development of mature female albino rats. Materials and Methods: Fifteen 8-week-old female Sprague-Dawley rats, at the diestrus stage of the estrus cycle, were divided into three different treatment groups: Control group (mineral water), bas-low group (1% of basil maceration), and bas-high group (5% of basil maceration). Basil maceration was dissolved and administered in mineral drinking water, and the treatments were given for 20 days (4 estrus cycles). At the end of the treatment period, serum follicle-stimulating hormone (FSH), estradiol, and progesterone (Pg) were measured using enzyme-linked immunosorbent assay. The relative weight of the ovary and uterus; diameter and length of uterine cornual; vascularization of uterus; the diameter of uterine glands; the number of primary, secondary, and tertiary de Graaf follicles; the number of corpora luteum; as well as the expression of vascular endothelial growth factor (VEGF) in the ovary were determined. Results: There was no significant difference (p>0.05) in the serum FSH level of rats treated with basil maceration drinking water doses of 1% and 5% compared to the control group. However, serum estradiol and Pg concentrations in the 1% and 5% basil maceration groups were significantly higher (p<0.05) than those of the control group. Furthermore, 1% and 5% basil maceration significantly increased the uterus's relative weight, diameter, and vascularization. Serum estradiol concentrations contributed to the elevated expression of VEGF compared to Pg. Conclusion: Administration of basil maceration for 20 days before mating could improve follicle growth and development, eventually increasing estradiol synthesis and secretion, thus improving the uterus's preparation for implantation. This makes basil maceration an attractive candidate in clinical research to enhance the growth and development of the uterus and placenta, which will better support the optimum prenatal growth and development of embryos and fetuses, resulting in superior offspring.

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Section: Discussionmentioning

confidence: 99%

Potential use of Indonesian basil (Ocimum basilicum) maceration to increase estradiol and progesterone synthesis and secretion to improve prenatal growth of offspring using female albino rats as an animal model

et al. 2022

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“…Peningkatan tersebut mendukung pembuktian bahwa ekstrak pituitari mengandung hormon FSH yang dapat digunakan sebagai agen superovulasi. Peningkatan konsentrasi estrogen setelah superovulasi sesuai dengan laporan Riesenberg et al [28] dan Andriyanto et al [29]. Konsentrasi puncak estrogen pada sapi potong dara yang diinduksi superovulasi dengan hCG adalah 46,0+11,0 pg/ml.…”

Section: Hasil Dan Pembahasanunclassified

Efek pemberian ekstrak pituitari sapi terhadap peningkatan jumlah folikel ovarium dan konsentrasi estradiol pada tikus putih (Rattus norvegicus)

Siregar¹,

Siregar

Akmal

et al. 2020

Livest. Anim. Res.

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Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak pituitari terhadap peningkatan jumlah folikel dan konsentrasi estradiol pada tikus putih. Metode: Dalam penelitian ini digunakan 10 ekor tikus putih (Rattus norvegicus) betina dewasa, galur wistar, berumur 3-4 bulan dengan bobot badan antara 200-250 g yang dibagi atas 2 kelompok. Pada kelompok kontrol, tikus diinjeksi dengan hormon PMSG (PG 600, Intervet, Boxmeer, Holland) 5 IU secara intraperitoneal. Pada kelompok perlakuan, tikus diinjeksi dengan ekstrak pituitari secara intraperitoneal selama 3 hari yakni 1,0; 0,5; dan 0,3 ml. Empat hari setelah perlakuan awal, sampel darah dikoleksi langsung dari jantung untuk pemeriksaan konsentrasi estradiol, kemudian tikus-tikus tersebut dikorbankan dengan cara dislokasio cervicalis untuk pemeriksaan mikroskopis ovarium. Penghitungan terhadap jumlah folikel dilakukan dengan menggunakan mikroskop cahaya. Penghitungan konsentrasi estradiol darah dilakukan dengan teknik enzyme-linked immunosorbent assay (ELISA). Data jumlah folikel dan konsentrasi estradiol dianalisis menggunakan uji T.

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“…Efficacy of norgestomet ear implants, progesterone injections, PGF 2α , and horse anterior pituitary extract in producing ovarian responses, embryo recovery, and fertilization rate in goats were compared, without significant differences being noted [66,67]. When the superovulation was used in field condition, most producers don’t want the ovulated follicles above the normal range, study showed that an increased dose of PMSG injection significantly increased the numbers, total diameters, and diameter of each dominant follicle and corpus luteum, and injection of 7.5 IU PMSG/kg body weight at the luteolytic stage could be applied to increase the secretion of pregnancy hormones without increasing the number of ovulating follicles and corpora lutea above the normal ranges [68].…”

Section: Embryo Technologiesmentioning

confidence: 99%

Research advances in reproduction for dairy goats

Luo

Wang

Sun

2019

Asian-Australas J Anim Sci

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Considerable progress in reproduction of dairy goats has been made, with advances in reproductive technology accelerating dairy goat production since the 1980s. Reproduction in goats is described as seasonal. The onset and length of the breeding season is dependent on various factors such as breed, climate, physiological stage, male effect, breeding system, and photoperiod. The reproductive physiology of goats was investigated extensively, including hypothalamic and pituitary control of the ovary related to estrus behavior and cyclicity etc. Photoperiodic treatments coupled with the male effect allow hormone-free synchronization of ovulation, but the kidding rate is still less than for hormonal treatments. Different protocols have been developed to meet the needs and expectations of producers; dairy industries are subject to growing demands for year round production. Hormonal treatments for synchronization of estrus and ovulation in combination with artificial insemination (AI) or natural mating facilitate out-of-season breeding and the grouping of the kidding period. The AI with fresh or frozen semen has been increasingly adopted in the intensive production system, this is perhaps the most powerful tool that reproductive physiologists and geneticists have provided the dairy goat industry with for improving reproductive efficiency, genetic progress and genetic materials transportation. One of the most exciting developments in the reproduction of dairy animals is embryo transfer (ET), the so-called second generation reproductive biotechnology following AI. Multiple ovulation and ET (MOET) program in dairy goats combining with estrus synchronization (ES) and AI significantly increase annual genetic improvement by decreasing the generation interval. Based on the advances in reproduction technologies that have been utilized through experiments and investigation, this review will focus on the application of these technologies and how they can be used to promote the dairy goat research and industry development in the future.

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Optimum dose and time of pregnant mare serum gonadotropin injections in Kacang goats to increase endogenous secretion of estrogen and progesterone without superovulation response

Cited by 8 publications

References 25 publications

Potential use of Indonesian basil (Ocimum basilicum) maceration to increase estradiol and progesterone synthesis and secretion to improve prenatal growth of offspring using female albino rats as an animal model

Potential use of Indonesian basil (Ocimum basilicum) maceration to increase estradiol and progesterone synthesis and secretion to improve prenatal growth of offspring using female albino rats as an animal model

Efek pemberian ekstrak pituitari sapi terhadap peningkatan jumlah folikel ovarium dan konsentrasi estradiol pada tikus putih (Rattus norvegicus)

Research advances in reproduction for dairy goats

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