Optoacoustic response of gold nanorods in soft phantoms using high-power diode laser assemblies at 870 and 905 nm

Leggio, Luca; Gawali, Sandeep Babu; Gallego, Daniel; Rodríguez, Sergio; Sanchez, M. Isabel; Carpintero, Guillermo; Lamela, Horacio

doi:10.1364/boe.8.001430

Cited by 8 publications

(5 citation statements)

References 32 publications

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“…Tomography systems would also benefit from improved SNR, depth of penetration, and imaging speed as well as further clinical evaluations more thoroughly investigating the potentials of low-cost PAT systems for disease diagnosis and monitoring. Contrast agents with strong absorption in the NIR wavelength range and suitable for in vivo imaging can also benefit clinical applications of low-cost PAI system [76] , [77] , [78] , [79] , [80] .…”

Section: Discussionmentioning

confidence: 99%

Photoacoustic imaging with low-cost sources; A review

Erfanzadeh

Zhu

2019

Photoacoustics

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Benefitting from advantages of optical and ultrasound imaging, photoacoustic imaging (PAI) has demonstrated potentials in a wide range of medical applications. In order to facilitate clinical applications of PAI and encourage its application in low-resource settings, research on low-cost photoacoustic imaging with inexpensive optical sources has gained attention. Here, we review the advances made in photoacoustic imaging with low-cost sources.

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Section: Discussionmentioning

confidence: 99%

Photoacoustic imaging with low-cost sources; A review

Erfanzadeh

Zhu

2019

Photoacoustics

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“…Moreover, the continuous modulation could facilitate the more low-cost imaging or sensing system since the required output power of the light source is much lower than the pulsed modulation. Fourthly, the contrast agent could be used to generate larger PA signal amplitude, such as gold and silver nanoparticles and gold nanorods [ 101 , 102 , 103 , 104 , 105 , 106 , 107 , 108 , 109 ]. Moreover, the double-walled carbon nanotubes could be used as nontoxic and biodegradable contrast agents [ 110 ].…”

Section: Discussionmentioning

confidence: 99%

Review of Low-Cost Photoacoustic Sensing and Imaging Based on Laser Diode and Light-Emitting Diode

Zhong

Duan

Lan

et al. 2018

Sensors

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Photoacoustic tomography (PAT), a promising medical imaging method that combines optical and ultrasound techniques, has been developing for decades mostly in preclinical application. A recent trend is to utilize the economical laser source to develop a low-cost sensing and imaging system, which aims at an affordable solution in clinical application. These low-cost laser sources have different modulation modes such as pulsed modulation, continuous modulation and coded modulation to generate different profiles of PA signals in photoacoustic (PA) imaging. In this paper, we review the recent development of the photoacoustic sensing and imaging based on the economical laser sources such as laser diode (LD) and light-emitting diode (LED) in different kinds of modulation types, and discuss several representative methods to improve the performance of such imaging systems based on low-cost laser sources. Finally, some perspectives regarding the future development of portable PAT systems are discussed, followed by the conclusion.

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“…Furthermore, development and application of photoacoustic contrast agents with absorption peaks near 905 nm can enhance the SNR and image quality of this system [70] , [71] , [72] , [73] , [74] . Studying skin and cervical cancer can be other possible applications of a laser scanning laser diode based PAM system [18] , [19] , [20] , [26] .…”

Section: Discussionmentioning

confidence: 99%

Laser scanning laser diode photoacoustic microscopy system

2018

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The development of low-cost and fast photoacoustic microscopy systems enhances the clinical applicability of photoacoustic imaging systems. To this end, we present a laser scanning laser diode-based photoacoustic microscopy system. In this system, a 905 nm, 325 W maximum output peak power pulsed laser diode with 50 ns pulsewidth is utilized as the light source. A combination of aspheric and cylindrical lenses is used for collimation of the laser diode beam. Two galvanometer scanning mirrors steer the beam across a focusing aspheric lens. The lateral resolution of the system was measured to be ∼21 μm using edge spread function estimation. No averaging was performed during data acquisition. The imaging speed is ∼370 A-lines per second. Photoacoustic microscopy images of human hairs, ex vivo mouse ear, and ex vivo porcine ovary are presented to demonstrate the feasibility and potentials of the proposed system.

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Optoacoustic response of gold nanorods in soft phantoms using high-power diode laser assemblies at 870 and 905 nm

Cited by 8 publications

References 32 publications

Photoacoustic imaging with low-cost sources; A review

Photoacoustic imaging with low-cost sources; A review

Review of Low-Cost Photoacoustic Sensing and Imaging Based on Laser Diode and Light-Emitting Diode

Laser scanning laser diode photoacoustic microscopy system

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