Oral candidiasis as a clinical marker related to viral load, CD4 lymphocyte count and CD4 lymphocyte percentage in HIV‐infected patients

Campo, Julián; Romero, Jorge del; Castilla, Jesús; Garcia, S.; Rodriguez, Carina A.; Bascones, A

doi:10.1034/j.1600-0714.2002.310102.x

Cited by 71 publications

(86 citation statements)

References 36 publications

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“…[30][31][32][33] However, this is consistent with the findings reported by other investigators. 29,34 We also observed a higher prevalence of PC in males than in females (17.7% and 10.6%, respectively; P <0.05). Patients with OC had 1.96 times higher chance of having their CD4 counts ≤200 than patients without OC.…”

Section: Discussionsupporting

confidence: 49%

Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients

Ranganathan¹,

Reddy²,

Kumarasamy³

et al. 2000

Oral Diseases

159

160

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BACKGROUND: Human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS) is a major health problem in India. The National AIDS Control Organisation (NACO) of India reports a seropositivity of 25.03 per thousand for the whole country, as of October 1999. In spite of this high prevalence there are very few reports of oral lesions and conditions in Indian HIV/AIDS patients, which are important in early diagnosis and management of these patients. OBJECTIVE AND SETTING: The present report describes the oral lesions in 300 HIV positive symptomatic patients presenting to us at RAGAS‐YRG CARE, a non‐governmental organisation in Chennai, South India, over a period of 9 months in 1998. METHOD: Lesions were diagnosed on clinical appearance using international criteria. RESULTS: Of the 300 patients 89% had acquired the infection through heterosexual contact. There were 205 males and 95 females, aged from 7 months to 72 years. Forty‐seven percent of the patients were in the age group 21–30 years. CD4 counts were ascertained for 105 patients, 64 (62%) had CD4 counts ≤200. A total of 217 (72%) of the 300 patients had some oral lesion when examined. Gingivitis (47%) and pseudomembranous candidiasis (33%) were the most common oral lesions. The other oral lesions seen were oral mucosal pigmentation (23%), erythematous candidiasis (14%), periodontitis (9%), angular cheilitis (8%), oral ulcers (3%), oral hairy leukoplakia (3%), hyperplastic candidiasis (1%), oral submucous fibrosis (2%) and one case of leukoplakia. CONCLUSIONS: Oral lesions occur commonly in HIV infection. A comprehensive oral examination may not only suggest HIV disease but may also be useful in monitoring the disease progression. This is a cost‐effective procedure, which may be useful in screening large populations in developing countries like India.

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Section: Discussionsupporting

confidence: 49%

Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients

Ranganathan¹,

Reddy²,

Kumarasamy³

et al. 2000

Oral Diseases

159

160

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“…Candida carriage lebih sering pada wanita, atau orang-orang dengan golongan darah O, diet tinggi karbohidrat, xerostomia, pengguna antimikroba spektrum luas (contoh: tetrasiklin), pemakai protesa gigi, perokok, kondisi immunocompromised (penyakit HIV, sindrom Down, malnutrisi, atau diabetes), dan pasien yang dirawat di rumah sakit. 2,4,5,6 Berbagai literatur telah banyak melaporkan hasil penelitian maupun laporan kasus terkait oral candidiasis, tetapi penelitian terutama dalam bidang Ilmu Penyakit Mulut di Indonesia masih Majalah Kedokteran Gigi Indonesia. April 2017; 3(1): 23 -28 ISSN 2460-0164 (print) ISSN 2442-2576 (online) belum banyak, sehingga penting untuk melakukan penelitian ini sebagai upaya menambah data awal mengenai prevalensi kandidiasis dan memberikan informasi yang berguna untuk peningkatan kesehatan masyarakat khususnya di bidang Ilmu Penyakit Mulut dan kesehatan mulut secara umum.…”

Section: Pendahuluanunclassified

“…Perawatan kandidiasis rongga mulut memerlukan identi kasi yang tepat, baik faktor predisposisi maupun kondisi sistemik yang menyebabkan kandidiasis. 2,4,5,18 . Sekitar 40,2% penderita candida pada penelitian ini terdapat riwayat penggunaan antibiotik dan obatabatan secara sistemik hal tersebut sesuai dengan literature yang menyebutkan bahwa kandidiasis biasanya berhubungan dengan terapi steroid jangka panjang, antibiotik spectrum luas, dan kondisi sitemik seperti de siensi nutrisi, diabetes mellitus, anemia/leukemia, dan HIV/AIDS.…”

Section: Pembahasanunclassified

Profil oral candidiasis di bagian ilmu penyakit mulut RSHS Bandung periode 2010-2014

Nur’aeny

Hidayat

Dewi

et al. 2017

Majalah Kedokteran Gigi Indonesia

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ABSTRAKCandida. albicans (C.albicans) merupakan agen penyebab primer pada oral candidiasis. Candida spp merupakan mikroorganisme komensal atau  ora normal dalam mulut dengan tanpa menimbulkan gejala. Candida spp dapat menjadi patogen saat kondisi daya tahan tubuh menurun terutama dalam kondisi penyakit autoimun yang diberikan terapi steroid karena steroid bersifat menurunkan sistem imun atau terapi obat-obatan secara sistemik dalam jangka waktu lama. Penelitian oral candidiasis di Indonesia masih belum banyak dilakukan. Penelitian ini bertujuan untuk mengetahui pro l oral candidiasis pada pasien-pasien yang ditangani di Bagian Penyakit Mulut di Rumah Sakit dr. Hasan Sadikin (RSHS), Bandung, Indonesia periode tahun 2010 -2014. Hasil penelitian menunjukkan selama periode 2010 hingga 2014 sebanyak 49 orang pasien yang datang ke klinik ilmu penyakit mulut ditemukan oral candidiasis. Prevalensi terbanyak adalah pria sebesar 34 orang (69,3%) dan wanita 15 orang (30,7%), dengan faktor predisposisi terbanyak adalah keterlibatan penyakit sistemik sebesar 40,2%. Lokasi paling sering ditemukan lesi plak pseudomembran putih dan terdapat di daerah dorsal lidah. Pro l kandidiasis pada pasien yang berkunjung ke klinik ilmu penyakit mulut RSHS secara garis besar umumnya disebabkan oleh kondisi sistemik, penyakit autoimun dan kebersihan rongga mulut yang buruk sedangkan untuk terapi kandidiasis, penggunaan nystatin masih efektif untuk digunakan mengobati kandidiasis. RSHS Bandung, Indonesia at 2010 -2014

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“…Prevalence of oral lesions has been shown to be significantly higher in individuals with a CD4+ count less than 200 cells/mm 3 and a viral load greater than 3000 copies/mL (Bravo et al, 2006;Greenspan et al, 2000;Tappuni & Fleming, 2001). The importance of oral lesions as clinical indicators of HIV infections and markers of clinical progression to AIDS has been demonstrated in many studies that reported their association with CD4+ depletion and high viral load (Bravo et al, 2006;Campo et al, 2002;Chattopadhyay et al, 2005;Glick et al, 1994;Greenspan et al, 2000;Patton, 2000;Ramírez-Amador et al, 2003;Shiboski et al, 2001). A comprehensive review of epidemiologic studies on HIV-related oral lesions reported from developed and developing countries over more than a decade, encompassing the pre-HAART and early-HAART period from 1986 to 2000, revealed oral candidiasis as the most common lesion found in all ages across the world (Patton et al, 2002).…”

Section: Epidemiology Of Hiv-associated Oral Manifestationsmentioning

confidence: 99%

Oral Health-Related Quality of Life Among People Living with HIV/AIDS

Saddki¹,

Mohamad²

2011

HIV-infection - Impact, Awareness and Social Implications of Living With HIV/AIDS

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Oral candidiasis as a clinical marker related to viral load, CD4 lymphocyte count and CD4 lymphocyte percentage in HIV‐infected patients

Cited by 71 publications

References 36 publications

Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients

Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients

Profil oral candidiasis di bagian ilmu penyakit mulut RSHS Bandung periode 2010-2014

Oral Health-Related Quality of Life Among People Living with HIV/AIDS

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