Oral chloral hydrate provides effective and safe sedation in paediatric magnetic resonance imaging

Ronchera-Oms, C L; Casillas, Carlos; Martí‐Bonmatí, Luis; Poyatos, C.; Tomás, Juan Carlos Sebastián; Sobejano, A.; Jiménez, N. V.

doi:10.1111/j.1365-2710.1994.tb00680.x

Cited by 48 publications

(20 citation statements)

References 13 publications

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“…However, most of the failures occurred in older children. 11,12 The high success rate in our study using oral chloral hydrate was probably due to restricting its use to patients less than 18 mo of age.…”

Section: Discussionmentioning

confidence: 96%

Trained nurses can provide safe and effective sedation for MRI in pediatric patients

Beebe

Tran

Bragg

et al. 2000

Can J Anesth/J Can Anesth

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Purpose: To determine the success rate, safety and complications using a standard protocol and trained nurses to provide sedation for MRI under the supervision of a radiologist. Materials and Methods:Nurses were trained to provide sedation via a standard protocol for pediatric patients undergoing diagnostic MRI. Oral chloral hydrate (80-100 mg·kg -1 ) was used for children less than 18 mo of age. Older children received either 1-6 mg·kg -1 pentobarbital iv, with or without 1-2 µg·kg·hr -1 fentanyl, or 25 mg·kg -1 thiopental pr. Sedation was defined as successful if it allowed completion of the MRI without image distorting patient movement. The records of 572 MRIs performed on 488 pediatric patients (mean age 5 ± 4 yr; age 2 mo-14 yr) from 1991 to July 1995 were reviewed to determine the success rate and complications using the sedation program.Results: Most, 91.8% (525/572), of the MRIs were successfully completed in 445 patients. The reasons for failure were inadequate sedation (45, 95.7%) and coughing (2, 4.2%). The failure rate was much higher before 1994 (38/272, 14%) than after (9/300, 3%; P < 0.0001). Failure was more common if rectal thiopental was used (23/172, 14%) than intravenous pentobarbital (19/256, 7.4%; P < 0.05). The failure rate was also high in patients with a history of a behavioural disorder (10/59,17%). There were no deaths or unexpected admissions as a result of the sedation program. Conclusion:A high success rate can be achieved as experience is gained using a standard protocol and trained nurses to sedate children for MRI. Méthode : Des infirmières ont été formées pour administrer la sédation selon un protocole standard à des patients pédiatriques devant subir un examen diagnostique d'IRM. L'hydrate de chloral oral (80-100 mg·kg -1 ) a servi pour les enfants de moins de 18 mois. Les plus âgés ont reçu soit 1-6 mg·kg -1 de pentobarbital iv, avec ou sans 1-2 µg·kg·hr -1 de fentanyl, soit 25 mg·kg -1 de thiopental pr. On considérait la sédation réussie quand l'IRM était achevé sans distorsion d'image par un mouvement du patient. Les enregistrements de 572 IRM réalisés chez 488 enfants (âge moyen de 5 ± 4 ans; limite d'âge de 2 mois-14 jrs) de 1991 à juillet 1995 ont été revus pour l'évaluation du taux de succès et des complications liés au programme de sédation.Résultats : La plupart des examens d 'IRM, 91,8 % (525/572), ont été réalisés avec succès chez 445 patients. Les échecs ont eu pour cause une sédation insuffisante (45, 95,7 %) et la toux (2, 4,2 %). Le taux d'échec a été beaucoup plus élevé avant 1994 (38/272, 14 %) qu'après (9/300, 3 %; P < 0,0001). L'échec était plus fréquent avec l'usage de thiopental rectal (23/172, 14 %) qu'avec le pentobarbital intraveineux (19/256, 7,4 %; P < 0,05). Le taux d'échec a été élevé également chez les patients qui présentaient des antécédents de troubles de comportement (10/59, 17 %). Aucun cas de décès ou d'admission imprévue n'a résulté de ce programme de sédation.Conclusion : Un fort taux de réussite peut être atteint à mesure que se développe l...

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Section: Discussionmentioning

confidence: 96%

Trained nurses can provide safe and effective sedation for MRI in pediatric patients

Beebe

Tran

Bragg

et al. 2000

Can J Anesth/J Can Anesth

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“…Rates of successful sedation with this medication range from 85% to 98% (5,6). Adverse events associated with chloral hydrate include oxygen desaturation, nausea, vomiting, hyperactivity, respiratory depression, and failed sedation (7). Until 1999, our radiology sedation protocol for infants younger than 1 year was limited to chloral hydrate administration.…”

mentioning

confidence: 98%

Adverse Cardiovascular and Respiratory Events during Sedation of Pediatric Patients for Imaging Examinations

Sanborn¹,

Michna²,

Zurakowski³

et al. 2005

Radiology

167

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“…Rates of successful sedation with this medication range from 85%-98% (5,6). Adverse events with chloral hydrate include oxygen desaturation, nausea, vomiting, hyperactivity, respiratory depression, and failure of adequate sedation (2,7). Until 1999, our radiology sedation protocol for infants younger than 1 year of age was limited to chloral hydrate.…”

mentioning

confidence: 98%

Superiority of Pentobarbital versus Chloral Hydrate for Sedation in Infants during Imaging

Mason¹,

Sanborn²,

Zurakowski³

et al. 2004

Radiology

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Oral chloral hydrate provides effective and safe sedation in paediatric magnetic resonance imaging

Cited by 48 publications

References 13 publications

Trained nurses can provide safe and effective sedation for MRI in pediatric patients

Trained nurses can provide safe and effective sedation for MRI in pediatric patients

Adverse Cardiovascular and Respiratory Events during Sedation of Pediatric Patients for Imaging Examinations

Superiority of Pentobarbital versus Chloral Hydrate for Sedation in Infants during Imaging

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