Orbitale MALT-Lymphome: Klinisch-pathologische Korrelation

Schröder-Frei, B; Kurrer, Michael; Chaloupka, Karla; Frei, J; Landau, K.

doi:10.1055/s-2006-926585

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…Coupland classified ocular adnexal lymphomas into 5 types according to REAL as follows: mucosa-associated lymphoid tissue lymphoma, follicular central lymphoma, diffuse large B-cell lymphoma, plasmacytoma, and Gonoctic lymphoma. Jenkins classified it into mucosa-associated lymphoid tissue lymphoma, plasmacytoid cell lymphoma, follicular central lymphoma, diffuse large B-cell lymphoma and other rare lymphomas [18]. The characteristics of ocular accessory lymphoma are that the cell morphology of lymphoma is a certain stage in the process of normal lymphocyte transformation with corresponding The morphological structure characteristics of histiocytes are the main elements of diagnosis, and immunomarkers and genetic detection play an important role in the differential diagnosis of lymphoma.…”

Section: Discussionmentioning

confidence: 99%

Orbital Lymphoproliferative Disorders (OLPDs) in a 3-year-old Child: Case Report and Review of Literature

Shi

Feng

Zhao

et al. 2023

Arch Clin Ophthalmol

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Background: Orbital lymphoproliferative disorders (OLPDs) consist of a spectrum of diseases ranging from benign to malignant lesions including reactive lymphoid hyperplasia, atypical lymphoid hyperplasia, and lymphoma. OLPDs rarely present as an orbital mass lesion in children. Accurate discrimination of OLPDs is crucial for treatment planning. We report a case to investigate the clinical and pathological features of OLPDs in children. Case presentation: A 3-year-old female with orbital mass was admitted to the hospital and proceeded to have a CT orbit which showed an orbital mass. The orbital mass was removed after operation and pathologic diagnosis was identified. Pathological diagnosis with histopathological features and immunohistochemical markers was lymphoproliferative lesion in the left orbit. The diagnosis was consistent with OLPDs. There was no recurrence after one-year follow-up. Conclusions: OLPDs are rare in children. The clinical manifestations and imaging have no specificity; pathological diagnosis with histopathological features and immunohistochemical markers is the main basis for the diagnosis and treatment.

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Section: Discussionmentioning

confidence: 99%

Orbital Lymphoproliferative Disorders (OLPDs) in a 3-year-old Child: Case Report and Review of Literature

Shi

Feng

Zhao

et al. 2023

Arch Clin Ophthalmol

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“…Die empfohlene Radiotherapiedosis ist unterschiedlich zwischen den verschiedenen Autoren. Einige Autoren empfehlen eine Dosis von 30 Gy bei niedrig malignen primären lokalisierten OL [12,14,15,17], andere eine Dosis von 35 Gy [7] oder sogar 36 -40 Gy [6]. [10,21,22], zeigten Langzeitbeobachtungen, dass extraorbitale Rezidive mit letalem Verlauf möglich sind [23,24].…”

Section: Abstract !unclassified

Die Strahlentherapie als Therapieoption bei primären lokalisierten niedrig malignen orbitalen Lymphomen

Manousaridis¹,

Beck²,

Klautke³

et al. 2010

Klin Monatsbl Augenheilkd

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Orbital lymphoma

Olsen

Heegaard

2019

Survey of Ophthalmology

173

187

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Orbital lymphomas constitute 50-60% of ocular adnexal lymphomas. A total of 2211 cases of orbital lymphoma with a known subtype have been reported in the last 24 years (1994-2017). The vast majority of orbital lymphomas are of B-cell origin (97%), of which extranodal marginal zone B-cell lymphoma (EMZL) (59%) is the most common subtype, followed by diffuse large B-cell lymphoma (23%), follicular lymphoma (9%), and mantle cell lymphoma (5%). Orbital lymphoma is primarily a disease of the elderly. Gender distribution varies according to lymphoma subtype. However, extranodal marginal zone B-cell lymphoma (53%) and follicular lymphoma (75%) show a female predominance, whereas diffuse large B-cell lymphoma shows an even gender distribution. Mantle cell lymphoma has a striking male predominance of 80%. The histopathological subtype and the clinical stage of the disease are the best indicators of prognosis and patient outcome. Low-grade lymphomas such as extranodal marginal zone B-cell lymphoma and FL have a good prognosis, whereas high-grade lymphomas (diffuse large B-cell lymphoma and mantle cell lymphoma) are associated with a poor prognosis. When managing solitary low-grade lymphomas, radiotherapy is the treatment of choice. Chemotherapy, with or without radiotherapy, should be chosen for disseminated and high-grade lymphomas.

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Orbitale MALT-Lymphome: Klinisch-pathologische Korrelation

Cited by 3 publications

References 4 publications

Orbital Lymphoproliferative Disorders (OLPDs) in a 3-year-old Child: Case Report and Review of Literature

Orbital Lymphoproliferative Disorders (OLPDs) in a 3-year-old Child: Case Report and Review of Literature

Die Strahlentherapie als Therapieoption bei primären lokalisierten niedrig malignen orbitalen Lymphomen

Orbital lymphoma

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