Oromucosal film preparations: classification and characterization methods

Preis, Maren; Woertz, Christina; Kleinebudde, Peter; Breitkreutz, Jörg

doi:10.1517/17425247.2013.804058

Cited by 124 publications

(80 citation statements)

References 82 publications

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“…Out of these transmucosal buccal films have been reported to be more flexible, comfortable with relatively longer residence time (than that of oral gels) on the mucosa. These films also show more protectant effect on the local wound surface for oral diseases [21][22][23].…”

Section: Introductionmentioning

confidence: 95%

See 1 more Smart Citation

Buccal Transmucosal Delivery System of Enalapril for Improved Cardiac Drug Delivery: Preparation and Characterization

He¹,

Xiong²,

Xi³

et al. 2016

Trop. J. Pharm Res

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Section: Introductionmentioning

confidence: 95%

“…Various TMDDS like tablets, films, patches, disks, strips, ointments and gels have been investigated [14][15][16][17][18][19][20][21]. Out of these transmucosal buccal films have been reported to be more flexible, comfortable with relatively longer residence time (than that of oral gels) on the mucosa.…”

Section: Introductionmentioning

confidence: 99%

Buccal Transmucosal Delivery System of Enalapril for Improved Cardiac Drug Delivery: Preparation and Characterization

He¹,

Xiong²,

Xi³

et al. 2016

Trop. J. Pharm Res

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“…Drying, depending on the technology chosen and the properties of the substances, is performed at room temperature or heating to 40-60°C, then the film is removed from the supporter and cut into pieces of the required size. [29][30][31] The solution can also be applied to the surface with a spray (in the form of spray), which allows to get very thin films, but such technology is difficult to exploit, provided that the viscosity of the disperse system is high and is more often used to produce quick-dissolving oral films.…”

Section: Technological Processmentioning

confidence: 99%

Untitled

Хохленкова

2017

AJP

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Introduction: Nowadays, biopolymers and biomaterials are an actively developing field, interesting both for specialists from various fields of science and for society at large. The range of polymers of both natural and synthetic origin is constantly expanding, but only a few of them are used in pharmaceutical production and medical practice. Due to the composition of polymers and active pharmaceutical ingredient, films are a promising form for applying in dentistry, ophthalmology, surgery, and other fields of medicine. Materials and Methods: In the work marketing and economic research methods are used to ground social and medical practicability of developing new dental products for local treatment. Results and Discussions: Based on the data of modern scientific literature, the requirements for medicinal films are outlined, their classification is given. Approaches to the choice of active and auxiliary substances in the process of developing new film formulations are described. The prospects of using films in surgery, dentistry, ophthalmology, and dermatology are shown. Conclusions: Based on the review, polymer films have been classified, and the requirements for the given dosage form have been defined. Approaches to selecting active and auxiliary ingredients have been considered. The main aspects of the technological process for the preparation of films are described. The ways of rational application of films in medical practice have been highlighted.

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“…Several methods have been developed to manufacture chitosan films, such as casting-solvent evaporation, hot-melt extrusion and printing method (Preis et al 2013). Among these methods, casting-solvent evaporation method is widely used because of its simple process (Juliano et al 2008).…”

Section: As Matrix Of Filmsmentioning

confidence: 99%

Drug Delivery Applications of Chitosan and its Derivatives

Zhang

Mao

2015

Excipient Applications in Formulation Design and Drug Delivery

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The development of drug delivery systems always goes hand in hand with the advancement of material science. The novel synthetic or natural functional materials provide opportunities to design optimal drug delivery systems. Among these, chitosan and its derivatives exhibit excellent application future because of its prominent characteristics. In this chapter, research progress of chitosan and its derivatives for drug delivery, from structure to properties, from properties to its application were overviewed. The physicochemical properties, biological properties, biodegradability, safety evaluation and structure modification of chitosan were introduced. Furthermore, applications of chitosan and its derivatives in drug delivery including as the carrier of nanoparticles and microparticles, as coating material, as matrix of hydrogels, films and sustained release tablets, as stabilizers, as absorption enhancers, were discussed. Finally, the applications of chitosan and its derivatives in different administration routes, and their advantages for gene, protein and vaccine delivery, were reviewed. The numerous successful studies on exploitation and application of chitosan and its derivatives showed promising application future of these materials in drug delivery.

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Oromucosal film preparations: classification and characterization methods

Cited by 124 publications

References 82 publications

Buccal Transmucosal Delivery System of Enalapril for Improved Cardiac Drug Delivery: Preparation and Characterization

Buccal Transmucosal Delivery System of Enalapril for Improved Cardiac Drug Delivery: Preparation and Characterization

Untitled

Drug Delivery Applications of Chitosan and its Derivatives

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